SCHEMBL25022660

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20777560	0.87	SMARCA2 (0.47)	SMARCA2SMARCA4BRD4ADRA1APDK2
	SCHEMBL31048702	0.85	BRD4 (0.54)	SMARCA2SMARCA4BRD4ADRA1APDK2
	SCHEMBL31181988	0.82	BRD4 (0.48)	SMARCA2SMARCA4BRD4ADRA1APDK2
	SCHEMBL20773248	0.80	CFD (0.52)	SMARCA2SMARCA4BRD4ADRA1APDK2
	SCHEMBL30332122	0.80	PDK2 (0.48)	DPP4BRD4PDK2
	SCHEMBL30332368	0.80	DPP4 (0.51)	DPP4PDK2FEN1PRMT5WDR77
	SCHEMBL23753803	0.78	ALK (0.46)	SMARCA2SMARCA4ALOX5APFEN1PRMT5
	SCHEMBL14863737	0.78	SMARCA2 (0.45)	SMARCA2SMARCA4BRD4ADRA1APDK2
	SCHEMBL10544187	0.77	SMARCA2 (0.60)	SMARCA2SMARCA4BRD4ADRA1APDK2
	SCHEMBL23638914	0.75	BRD4 (0.54)	SMARCA2SMARCA4BRD4ADRA1APDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.