Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24939910 | 0.90 | HTR6 (0.41) | TSHRACHEGPR84FAAHDPP8 | |
| SCHEMBL23334525 | 0.86 | TSHR (0.37) | TSHRACHEGPR84FAAHDPP8 | |
| SCHEMBL28980925 | 0.85 | KDM4E (0.50) | TSHRACHEGPR84FAAHMEN1 | |
| SCHEMBL28980935 | 0.84 | KDM4E (0.47) | MEN1KMT2AHTR1A | |
| SCHEMBL30337432 | 0.83 | ALDH1A1 (0.46) | TSHRMEN1KMT2ADRD2DRD3 | |
| SCHEMBL24939934 | 0.82 | CYP2D6 (0.56) | TSHRDRD2DRD4DRD3 | |
| SCHEMBL24939864 | 0.81 | CHRNA7 (0.49) | FAAHDRD2DRD4DRD3OPRM1 | |
| SCHEMBL24152329 | 0.80 | GSK3B (0.50) | DRD2SIGMAR1 | |
| SCHEMBL24938955 | 0.80 | LMNA (0.49) | TSHRGPR84MEN1KMT2ADRD2 | |
| SCHEMBL30336973 | 0.79 | KMT2A (0.49) | ACHEFAAHMEN1KMT2ADRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |