Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
| ▸ | GBA1 | P04062 | 2/20 | 0.30 |
| ▸ | UGCG | Q16739 | 2/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337109 | 0.85 | TSHR (0.47) | FAAHMEN1KMT2ATSHRGPR84 | |
| SCHEMBL30337245 | 0.79 | HTR1A (0.47) | KDM4EPOLBHTTALDH1A1FAAH | |
| SCHEMBL30337432 | 0.78 | ALDH1A1 (0.46) | POLBALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL24939910 | 0.77 | HTR6 (0.41) | ALDH1A1FAAHMEN1KMT2ATSHR | |
| SCHEMBL30336973 | 0.76 | KMT2A (0.49) | POLBFAAHMEN1KMT2AACHE | |
| SCHEMBL28980935 | 0.76 | KDM4E (0.47) | KDM4EPOLBHTTALDH1A1MEN1 | |
| SCHEMBL30337569 | 0.76 | KDM4E (0.46) | KDM4EPOLBHTTALDH1A1FAAH | |
| SCHEMBL30337145 | 0.76 | KDM4E (0.45) | KDM4EPOLBHTTALDH1A1FAAH | |
| SCHEMBL24152329 | 0.75 | GSK3B (0.50) | ALDH1A1 | |
| SCHEMBL24939934 | 0.75 | CYP2D6 (0.56) | KDM4EPOLBHTTALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |