Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 6/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337395 | 0.81 | SCN9A (0.35) | FAAHDRD4 | |
| SCHEMBL28980917 | 0.80 | FAAH (0.48) | FAAH | |
| SCHEMBL30336973 | 0.80 | KMT2A (0.49) | FAAHDRD4OPRL1OPRM1 | |
| SCHEMBL24153446 | 0.79 | FAAH (0.43) | HTR1AHTR7FAAHDRD4HCRTR1 | |
| SCHEMBL24152329 | 0.78 | GSK3B (0.50) | — | |
| SCHEMBL28980935 | 0.77 | KDM4E (0.47) | HTR1A | |
| SCHEMBL30337109 | 0.77 | TSHR (0.47) | HTR1AFAAHDRD4OPRL1OPRM1 | |
| SCHEMBL30337156 | 0.75 | CHKA (0.50) | FAAHHCRTR1HCRTR2 | |
| SCHEMBL30337432 | 0.75 | ALDH1A1 (0.46) | HTR1AHTR7HCRTR1HCRTR2OPRL1 | |
| SCHEMBL28980925 | 0.75 | KDM4E (0.50) | HTR1AFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |