Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CCR5 | P51681 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24145803 | 0.88 | ENPP2 (0.48) | ALDH1A1TSHRENPP2CCR5CYP2D6 | |
| SCHEMBL30337246 | 0.87 | ENPP2 (0.47) | ENPP2CCR5CYP2D6L3MBTL1SMN1; SMN2 | |
| SCHEMBL30337139 | 0.86 | MCHR1 (0.42) | LMNADDB1CRBN | |
| SCHEMBL24145684 | 0.83 | FAAH (0.39) | ALDH1A1TSHRENPP2CCR5CYP2D6 | |
| SCHEMBL30337200 | 0.83 | FAAH (0.39) | ALDH1A1TSHRENPP2CCR5CYP2D6 | |
| SCHEMBL30337505 | 0.83 | ALDH1A1 (0.46) | ALDH1A1KDM4EMAPTMAPK1ENPP2 | |
| SCHEMBL30337153 | 0.82 | FAAH (0.48) | EGLN1 | |
| SCHEMBL30337582 | 0.81 | SMN1; SMN2 (0.45) | TSHRPOLBSIGMAR1CYP2D6L3MBTL1 | |
| SCHEMBL30337060 | 0.81 | KMT2A (0.49) | ENPP2 | |
| SCHEMBL30337191 | 0.79 | HTR1A (0.47) | TSHRENPP2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |