Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | GLS | O94925 | 6/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29392091 | 0.87 | GPR139 (0.46) | TRPM8GLSGPR139 | |
| SCHEMBL17295978 | 0.87 | GPR139 (0.46) | TRPM8GLSGPR139 | |
| SCHEMBL29017154 | 0.87 | GPR139 (0.46) | TRPM8GLSGPR139 | |
| SCHEMBL29543522 | 0.83 | L3MBTL1 (0.63) | TRPM8L3MBTL1 | |
| SCHEMBL27649238 | 0.82 | TRPM8 (0.49) | TRPM8L3MBTL1EPHX1GPR139 | |
| SCHEMBL7470004 | 0.79 | TRPM8 (0.49) | TRPM8EPHX1GPR139 | |
| SCHEMBL31177417 | 0.77 | GPR139 (0.45) | TRPM8EPHX1GPR139 | |
| SCHEMBL12895271 | 0.77 | L3MBTL1 (0.68) | TRPM8L3MBTL1EPHX1GPR139 | |
| SCHEMBL17761208 | 0.76 | PLA2G10 (0.53) | TRPM8L3MBTL1EPHX1GPR139 | |
| SCHEMBL12895166 | 0.76 | PLA2G10 (0.53) | TRPM8L3MBTL1EPHX1GPR139 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594683-A | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |