Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472717 | 0.88 | TRPM8 (0.45) | TRPM8ALDH1A1GAAMAPTHPGD | |
| SCHEMBL1566068 | 0.82 | GPR139 (0.45) | ALDH1A1GAAMAPTHPGDALOX15 | |
| SCHEMBL27649238 | 0.82 | TRPM8 (0.49) | TRPM8EPHX1GPR139 | |
| SCHEMBL7473087 | 0.81 | EPHX1 (0.48) | EPHX1ALDH1A1GAAMAPTSCN9A | |
| SCHEMBL10624651 | 0.80 | L3MBTL1 (0.59) | TRPM8ALDH1A1 | |
| SCHEMBL30337490 | 0.79 | TRPM8 (0.47) | TRPM8EPHX1GPR139 | |
| SCHEMBL20349584 | 0.78 | KAT6A (0.49) | TRPM8EPHX1GPR139 | |
| SCHEMBL18945971 | 0.77 | TRPM8 (0.47) | TRPM8EPHX1NOTUMGPR139CTSA | |
| SCHEMBL31177472 | 0.77 | TRPM8 (0.47) | TRPM8EPHX1NOTUMGPR139CTSA | |
| SCHEMBL21272703 | 0.77 | TRPM8 (0.47) | TRPM8EPHX1NOTUMGPR139CTSA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077701-A4 | ANTI-VIRAL COMPOUNDS | LILLY CO ELI (US) | 2002-03-20 | — | — | EP | disclosed |
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| EP-1077701-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059587-A1 | ANTI-VIRAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1999-11-25 | — | — | WO | disclosed |