Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337166 | 0.94 | KDM4E (0.43) | KDM4EPOLBHTTFAAHALDH1A1 | |
| SCHEMBL30337582 | 0.83 | SMN1; SMN2 (0.45) | POLBHTR1ATHRBKMT2ASMN1; SMN2 | |
| SCHEMBL30337245 | 0.82 | HTR1A (0.47) | KDM4EPOLBHTTFAAHALDH1A1 | |
| SCHEMBL30337145 | 0.82 | KDM4E (0.45) | KDM4EPOLBHTTFAAHALDH1A1 | |
| SCHEMBL30336976 | 0.81 | KMT2A (0.55) | FAAHHTR1AKMT2AMEN1 | |
| SCHEMBL30337300 | 0.80 | HTR1A (0.45) | KDM4EPOLBALDH1A1HTR1ATHRB | |
| SCHEMBL30337191 | 0.78 | HTR1A (0.47) | HTR1ATHRBKMT2AMEN1 | |
| SCHEMBL24939928 | 0.78 | HTR1A (0.43) | ALDH1A1HTR1AKMT2AMEN1LMNA | |
| SCHEMBL30337246 | 0.78 | ENPP2 (0.47) | HTR1ATHRBKMT2ASMN1; SMN2 | |
| SCHEMBL24938893 | 0.77 | CYP19A1 (0.43) | POLBHTR1AKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |