Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337245 | 0.85 | HTR1A (0.47) | KDM4EPOLBHTTALDH1A1FAAH | |
| SCHEMBL30337569 | 0.82 | KDM4E (0.46) | KDM4EPOLBHTTALDH1A1FAAH | |
| SCHEMBL30337166 | 0.79 | KDM4E (0.43) | KDM4EPOLBHTTALDH1A1FAAH | |
| SCHEMBL30337111 | 0.76 | FAAH (0.43) | FAAH | |
| SCHEMBL28980925 | 0.76 | KDM4E (0.50) | KDM4EPOLBHTTALDH1A1FAAH | |
| SCHEMBL30336976 | 0.68 | KMT2A (0.55) | FAAHHTR1AKMT2A | |
| SCHEMBL30337119 | 0.67 | HTR1A (0.48) | KDM4EPOLBALDH1A1HTR1A | |
| SCHEMBL30337305 | 0.67 | HTR1A (0.43) | KDM4EPOLBALDH1A1HTR1AKMT2A | |
| SCHEMBL30337142 | 0.65 | SIGMAR1 (0.42) | ALDH1A1HTR1AMAPTKMT2A | |
| SCHEMBL24939947 | 0.65 | KMT2A (0.41) | HTTALDH1A1HTR1AHDAC6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916206-A | Novel compound and pharmaceutical composition for preventing or treating resistant cancer comprising same | 治愈医药社株式会社 | 2023-04-04 | — | — | CN | disclosed |