Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22455074 | 0.84 | NCF1 (0.64) | NCF1ALDH1A1GAAHTT | |
| SCHEMBL29354433 | 0.84 | NCF1 (0.64) | NCF1ALDH1A1GAAHTT | |
| SCHEMBL22395599 | 0.80 | ALDH1A1 (0.56) | NCF1ALDH1A1LMNACES2GAA | |
| SCHEMBL6636311 | 0.79 | NCF1 (1.00) | NCF1GAAHSD17B10 | |
| SCHEMBL22495842 | 0.78 | ADRB2 (0.58) | NCF1ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL22395799 | 0.77 | ALDH1A1 (0.68) | ALDH1A1LMNACES2KDM4EPOLB | |
| SCHEMBL4273949 | 0.76 | KDM4E (0.59) | ALDH1A1LMNACES2KDM4EHPGD | |
| SCHEMBL14539369 | 0.76 | ALDH1A1 (0.45) | NCF1ALDH1A1LMNAKDM4ENPSR1 | |
| SCHEMBL1223373 | 0.76 | NCF1 (0.64) | NCF1ALDH1A1LMNAGAAKDM4E | |
| SCHEMBL22395854 | 0.76 | ALDH1A1 (0.68) | ALDH1A1LMNACES2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230079399-A1 | SUBSTITUTED QUINOLINE ANALOGS AS ALDEHYDE DEHYDROGENASE 1A1 (ALDH1A1) INHIBITORS | THE US SECRETARY DEPARTMENT OF H (US) | 2023-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230079399-A1 | SUBSTITUTED QUINOLINE ANALOGS AS ALDEHYDE DEHYDROGENASE 1A1 (ALDH1A1) INHIBITORS | ALDH1A1, ALDH1A2, ALDH2 | NCF1 600/4885ALDH1A1 1/4885LMNA 4401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.