Sugi Predict

Sugi Predict / Compounds / SCHEMBL1036779

SCHEMBL1036779

SCHEMBL1036779

CC(=O)Nc1cccc(S(=O)(=O)Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ PKM P14618 3/20 0.57
▸ ALDH1A1 P00352 4/20 0.56
▸ HSD17B10 Q99714 2/20 0.56
▸ CYP1A2 P05177 1/20 0.56
▸ POLB P06746 1/20 0.51
▸ NR4A1 P22736 1/20 0.51
▸ RAB9A P51151 1/20 0.51
▸ SMN1; SMN2 Q16637 2/20 0.51
▸ LMNA P02545 1/20 0.51
▸ L3MBTL1 Q9Y468 1/20 0.50
▸ NAPRT Q6XQN6 1/20 0.50
▸ NPC1 O15118 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10788098 0.86 LMNA (0.68) PKMALDH1A1HSD17B10CYP1A2POLB
SCHEMBL18614198 0.84 CA1 (0.53) PKMALDH1A1HSD17B10POLBSMN1; SMN2
SCHEMBL30266262 0.84 ALDH1A1 (0.58) PKMALDH1A1HSD17B10CYP1A2POLB
SCHEMBL15461385 0.84 ALDH1A1 (0.58) PKMALDH1A1HSD17B10CYP1A2POLB
SCHEMBL3033845 0.84 PKM (0.58) PKMALDH1A1HSD17B10CYP1A2POLB
SCHEMBL7495027 0.83 CA1 (0.69) POLB
SCHEMBL3022743 0.83 PKM (0.57) PKMALDH1A1HSD17B10CYP1A2POLB
Water SCHEMBL11091187 0.83 PKM (0.57) PKMALDH1A1HSD17B10CYP1A2POLB
SCHEMBL7495022 0.83 PKM (0.57) PKMALDH1A1HSD17B10CYP1A2POLB
SCHEMBL949134 0.81 CA2 (0.53) PKMALDH1A1POLBRAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4356456-A — — None — — JP disclosed
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof MBD Co., Ltd. (KR) 2026-04-28 — — US disclosed
US-12479821-B2 Quinoline compound and use thereof MBD Co., Ltd. (KR) 2025-11-25 — — US disclosed
EP-3728194-B1 QUINOLINE SULFONAMIDE COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS OTAGO INNOVATION LTD (NZ) 2025-06-04 — — EP disclosed
US-20240287032-A1 NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF MBD Co., Ltd. (KR) 2024-08-29 — — US disclosed
US-12065421-B2 Inhibitors of oplophorus luciferase-derived bioluminescent complexes PROMEGA CORPORATION (US) 2024-08-20 — — US disclosed
EP-4140991-B1 INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES PROMEGA CORP (US) 2024-05-15 — — EP disclosed
WO-2023202583-A1 FXR REGULATOR AND USE THEREOF 北京大学 2023-10-26 — — WO disclosed
CN-116903559-A FXR modulators and uses thereof 北京大学 2023-10-20 — — CN disclosed
US-11691949-B2 Quinoline sulfonamide compounds and their use as antibacterial agents OTAGO INNOVATION LIMITED (NZ) 2023-07-04 — — US disclosed
EP-0352222-B1 Fibre-reactive formazane dyes, process for their preparation and their use CIBA GEIGY AG (CH) 1994-05-25 — — EP disclosed
WO-1994005639-A1 SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE VERTEX PHARMACEUTICALS INCORPORATED (US) 1994-03-17 — — WO disclosed
JP-H04356456-A PRODUCTION OF N-ACETYLAMINOARYLSULFONIC ACID CHLORIDE HOECHST AG 1992-12-10 — — JP disclosed
US-5114430-A Colorfast dyes that react with fibers to form red, orange or red color CIBA-GEIGY CORPORATION (US) 1992-05-19 — — US disclosed
US-4994562-A Colorfast; for dyeing wool, silk CIBA-GEIGY CORPORATION (US) 1991-02-19 — — US disclosed
EP-0352222-A2 Fibre-reactive formazane dyes, process for their preparation and their use CIBA-GEIGY AG (CH) 1990-01-24 — — EP disclosed
EP-0095177-B1 PROCESS FOR THE PREPARATION OF N-ACETYLAMINO-ARYL-SULPHONIC ACIDS HOECHST AKTIENGESELLSCHAFT (DE) 1985-07-24 — — EP disclosed
US-4487725-A Process for the preparation of N-acetylaminoarylsulfonic acids in sulfuric acid as solvent HOECHST AKTIENGESELLSCHAFT (DE) 1984-12-11 — — US disclosed
EP-0095177-A1 Process for the preparation of N-acetylamino-aryl-sulphonic acids HOECHST AKTIENGESELLSCHAFT (DE) 1983-11-30 — — EP disclosed
US-4394129-A WOOL, POLYAMIDES HOECHST AKTIENGESELLSCHAFT (DE) 1983-07-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287032-A1 NOVEL HETEROCYCLIC COMPOUND AND USE THEREOF CYP4B1, CYP4A11, CYP3A4 PKM 1276/4885ALDH1A1 268/4885HSD17B10 85/4885
US-12479821-B2 Quinoline compound and use thereof CYP4A11, CYP7A1, CYP4B1 PKM 1924/4885ALDH1A1 647/4885HSD17B10 65/4885
US-12612384-B2 Heterocyclic CYP4A inhibitor compounds and compositions thereof CYP4A11, CYP4B1, CYP4A22 PKM 1930/4885ALDH1A1 217/4885HSD17B10 65/4885
US-11691949-B2 Quinoline sulfonamide compounds and their use as antibacterial agents NQO2, SDHA, SIRT5 PKM 4293/4885ALDH1A1 2384/4885HSD17B10 2498/4885
US-12065421-B2 Inhibitors of oplophorus luciferase-derived bioluminescent complexes LUC7L2, LYPLAL1, GUSB PKM 3809/4885ALDH1A1 1554/4885HSD17B10 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.