Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | TSHR | P16473 | 6/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CD44 | P16070 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL34364 | 0.86 | POLB (0.48) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| SCHEMBL29366969 | 0.86 | POLB (0.48) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| Sulfuric Acid SCHEMBL17847416 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| Sulfuric Acid SCHEMBL2386170 | 0.84 | ALDH1A1 (0.41) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL10761313 | 0.84 | POLB (0.46) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL5183951 | 0.84 | POLB (0.46) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| Methane SCHEMBL701905 | 0.84 | POLB (0.46) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| Carbamic Acid SCHEMBL8735463 | 0.83 | TDP1 (0.41) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| SCHEMBL29087964 | 0.79 | CD44 (0.42) | ALDH1A1TSHRCYP3A4MAPTKDM4E | |
| SCHEMBL29087953 | 0.79 | POLB (0.42) | ALDH1A1TSHRCYP3A4MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115902024-A | Stable isotope labeling and liquid chromatography mass spectrometry combined analysis method for dye for strong reducibility limitation in hair dye | 甘肃省药品检验研究院 | 2023-04-04 | — | — | CN | claimed |
| CN-115902024-A | Stable isotope labeling and liquid chromatography mass spectrometry combined analysis method for dye for strong reducibility limitation in hair dye | 甘肃省药品检验研究院 | 2023-04-04 | — | — | CN | disclosed |