Sulfuric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRA2A ADRA2B ADRA2C ADRB1 ADRB2 ADRB3 CALCRL CHRM1 CHRM2 CHRM3 F2R MAOA MAOB MAP2K1 MAP2K2 NTRK1 NTRK2 NTRK3 OPRD1 OPRK1 OPRM1 P2RY12 PKLR SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SLC18A2 SLC6A2 SLC6A3 TLR7 TLR9 TUBA1A TUBA1B TUBA1C TUBA3C TUBA3E TUBA4A TUBB TUBB1 TUBB2A TUBB2B TUBB3 TUBB4A TUBB4B TUBB6 TUBB8 dacA dacB dacC folA ftsI mrcA mrcB mrdA pol rplA rplB rplC rplD rplE rplF rplI rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmB1 rpmB2 rpmC rpmD rpmE rpmE2 rpmF rpmG rpmG1 rpmG2 rpmH rpmI rpmJ rpmJ2 rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsR1 rpsR2 rpsS rpsT rpsU rpsZ ykgM ykgO

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	9/20	0.41

▸	TSHR	P16473	6/20	0.41

▸	CYP3A4	P08684	5/20	0.41

▸	HPGD	P15428	3/20	0.41

▸	HSD17B10	Q99714	3/20	0.41

▸	CASP1	P29466	3/20	0.41

▸	THRB	P10828	3/20	0.41

▸	MAPT	P10636	2/20	0.41

▸	KDM4E	B2RXH2	2/20	0.41

▸	GAA	P10253	2/20	0.41

▸	ALOX15	P16050	2/20	0.41

▸	RECQL	P46063	2/20	0.41

▸	MEN1	O00255	2/20	0.41

▸	KMT2A	Q03164	2/20	0.41

▸	PKM	P14618	1/20	0.41

▸	RAB9A	P51151	1/20	0.41

▸	PIK3CA	P42336	1/20	0.39

▸	TDP1	Q9NUW8	3/20	0.38

▸	TDP2	O95551	1/20	0.37

▸	NSD2	O96028	1/20	0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Sulfuric Acid SCHEMBL17847416	1.00	ALDH1A1 (0.41)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
SCHEMBL11650509	0.93	KEAP1 (0.42)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
Sulfuric Acid SCHEMBL2561125	0.91	ALDH1A1 (0.46)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
SCHEMBL5150922	0.88	ALDH1A1 (0.36)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
Trifluoromethanesulfonic Acid SCHEMBL3637583	0.86	ALDH1A1 (0.38)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
Trifluoromethanesulfonic Acid SCHEMBL29486332	0.86	ALDH1A1 (0.38)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
SCHEMBL33509	0.85	CYP3A4 (0.50)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
Sulfuric Acid SCHEMBL28948989	0.85	TDP2 (0.46)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
Sulfuric Acid SCHEMBL30338570	0.84	ALDH1A1 (0.39)	ALDH1A1TSHRCYP3A4HPGDHSD17B10
Bicarbonate SCHEMBL8746323	0.84	TDP1 (0.43)	ALDH1A1TSHRCYP3A4HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-20110224458-A1	PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE	NOVUS INTERNATIONAL INC. (US)	2011-09-15	—	—	US	claimed
US-10435566-B2	Particles for electrophoretic displays	MERCK PATENT GMBH (DE)	2019-10-08	—	—	US	disclosed
EP-3233944-B1	PARTICLES FOR ELECTROPHORETIC DISPLAYS	MERCK PATENT GMBH (DE)	2019-09-04	—	—	EP	disclosed
US-20180037744-A1	PARTICLES FOR ELECTROPHORETIC DISPLAYS	E INK CORPORATION	2018-02-08	—	—	US	disclosed
EP-3233944-A1	PARTICLES FOR ELECTROPHORETIC DISPLAYS	Merck Patent GmbH (DE)	2017-10-25	—	—	EP	disclosed
WO-2016096091-A1	PARTICLES FOR ELECTROPHORETIC DISPLAYS	MERCK PATENT GMBH (DE)	2016-06-23	—	—	WO	disclosed
WO-2014154871-A1	DYEING PROCESS USING AN IRIDOID COMPOUND AND DEVICES FOR THE SAME	L'OREAL (FR)	2014-10-02	—	—	WO	disclosed
US-8742170-B2	Preparation of methionine or selenomethionine from homoserine via a 4-substituted 2-aminobutanoic acid intermediate	NOVUS INTERNATIONAL, INC. (US)	2014-06-03	—	—	US	disclosed
US-20110224458-A1	PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE	NOVUS INTERNATIONAL INC. (US)	2011-09-15	—	—	US	disclosed
WO-2010118274-A1	PREPARATION OF 6-KETO, 3-ALKOXY MORPHINANS	MALLINCKRODT INC. (US)	2010-10-14	—	—	WO	disclosed
US-20100261906-A1	Preparation of 6-Keto, 3-Alkoxy Morphinans	MALLINCKRODT INC. (US)	2010-10-14	—	—	US	disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

Patent	Title	Text reads most about	Predicted target · text-rank
US-20180037744-A1	PARTICLES FOR ELECTROPHORETIC DISPLAYS	RAB5IF, GYPA, SELP	ALDH1A1 2363/4885TSHR 3669/4885CYP3A4 4011/4885
US-10435566-B2	Particles for electrophoretic displays	RAB5IF, SELP, SELE	ALDH1A1 2283/4885TSHR 3506/4885CYP3A4 4195/4885
US-20100261906-A1	Preparation of 6-Keto, 3-Alkoxy Morphinans	FASN, CYP2D6, CYP2B6	ALDH1A1 555/4885TSHR 4531/4885CYP3A4 15/4885
US-20110224458-A1	PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A 4-SUBSTITUTED 2-AMINOBUTANOIC ACID INTERMEDIATE	MTR, CBS, ABAT	ALDH1A1 2793/4885TSHR 2605/4885CYP3A4 646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.