SCHEMBL30338779

SCHEMBL30338779

FC(F)(F)c1ccc(/C=N/Cc2ccc(C(F)(F)F)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CA2 P00918 6/20 0.51
CA1 P00915 3/20 0.50
GRIN1 Q05586 1/20 0.48
GRIN2B Q13224 1/20 0.48
LMNA P02545 3/20 0.44
ALDH1A1 P00352 1/20 0.44
BCHE P06276 2/20 0.43
ACHE P22303 2/20 0.43
BACE1 P56817 2/20 0.43
TAAR1 Q96RJ0 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
IDO1 P14902 2/20 0.41
PTGS2 P35354 2/20 0.41
PTGS1 P23219 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11984375 0.91 BCHE (0.53) CA2CA1GRIN1GRIN2BLMNA
SCHEMBL2585051 0.78 ALDH1A1 (0.49) CA2CA1GRIN1GRIN2BALDH1A1
SCHEMBL2585050 0.78 ALDH1A1 (0.49) CA2CA1GRIN1GRIN2BALDH1A1
SCHEMBL20871103 0.76 LMNA (0.49) LMNAALDH1A1BCHEACHEBACE1
SCHEMBL7791260 0.74 LMNA (0.41) GRIN1GRIN2BLMNAALDH1A1BCHE
SCHEMBL8989191 0.74 IDO1 (0.43) GRIN1GRIN2BALDH1A1TAAR1IDO1
SCHEMBL7791265 0.74 LMNA (0.41) GRIN1GRIN2BLMNAALDH1A1BCHE
SCHEMBL28205339 0.74 CA1 (0.45) CA2CA1LMNAALDH1A1MAPT
SCHEMBL28964164 0.74 CA2 (0.63) CA2CA1GRIN1GRIN2BLMNA
SCHEMBL20200244 0.74 SMN1; SMN2 (0.54) CA2CA1GRIN1GRIN2BALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115894288-A Synthesis method of imine compound 枣庄学院 2023-04-04 CN disclosed