Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2585051 | 1.00 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL20200243 | 0.91 | NFE2L2 (0.52) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL19233522 | 0.91 | NFE2L2 (0.52) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL19233525 | 0.90 | CA2 (0.58) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL13133352 | 0.90 | GRIN1 (0.55) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL19233526 | 0.86 | NFE2L2 (0.56) | ALDH1A1MAPTSMN1; SMN2MEN1POLB | |
| SCHEMBL19439614 | 0.79 | GRIN2D (0.47) | ALDH1A1MAPTSMN1; SMN2KMT2ACA2 | |
| SCHEMBL20200244 | 0.78 | SMN1; SMN2 (0.54) | ALDH1A1MAPTSMN1; SMN2KDM4EMEN1 | |
| SCHEMBL20204446 | 0.78 | MAOB (0.50) | MAPTSMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL30338779 | 0.78 | CA2 (0.51) | ALDH1A1MAPTSMN1; SMN2CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10335775-B2 | Magnetically separable iron-based heterogeneous catalysts for dehydrogenation of alcohols and amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-07-02 | — | — | US | disclosed |
| US-20180147568-A1 | MAGNETICALLY SEPARABLE IRON-BASED HETEROGENEOUS CATALYSTS FOR DEHYDROGENATION OF ALCOHOLS AND AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-05-31 | — | — | US | disclosed |
| EP-1953158-B1 | BICYCLIC CINNAMIDE COMPOUND | EISAI R&D MAN CO LTD (JP) | 2012-09-12 | — | — | EP | disclosed |
| US-8048878-B2 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2011-11-01 | — | — | US | disclosed |
| US-7618960-B2 | Morpholine type cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-11-17 | — | — | US | disclosed |
| US-20090181945-A1 | TWO CYCLIC CINNAMIDE COMPOUND | KIMURA TEIJI | 2009-07-16 | — | — | US | disclosed |
| EP-1953154-A1 | MORPHOLINE TYPE CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2008-08-06 | — | — | EP | disclosed |
| EP-1953158-A1 | BICYCLIC CINNAMIDE COMPOUND | Eisai R&D Management Co., Ltd. (JP) | 2008-08-06 | — | — | EP | disclosed |
| US-20070117798-A1 | Morpholine type cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. | 2007-05-24 | — | — | US | disclosed |
| US-20070117839-A1 | Two cyclic cinnamide compound | EISAI R&D MANAGEMENT CO., LTD. | 2007-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147568-A1 | MAGNETICALLY SEPARABLE IRON-BASED HETEROGENEOUS CATALYSTS FOR DEHYDROGENATION OF ALCOHOLS AND AMINES | ADH1A, ADH1C, ADH5 | ALDH1A1 97/4885MAPT 1746/4885SMN1; SMN2 1593/4885 |
| US-20090181945-A1 | TWO CYCLIC CINNAMIDE COMPOUND | APP, BACE1, PSEN1 | ALDH1A1 869/4885MAPT 160/4885SMN1; SMN2 119/4885 |
| US-20070117798-A1 | Morpholine type cinnamide compound | MLX, XDH, NOX4 | ALDH1A1 785/4885MAPT 3321/4885SMN1; SMN2 642/4885 |
| US-20070117839-A1 | Two cyclic cinnamide compound | APP, BACE1, PSEN1 | ALDH1A1 869/4885MAPT 160/4885SMN1; SMN2 119/4885 |
| US-10335775-B2 | Magnetically separable iron-based heterogeneous catalysts for dehydrogenation of alcohols and amines | ADH1A, ADH1C, ADH5 | ALDH1A1 97/4885MAPT 1746/4885SMN1; SMN2 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.