Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.50 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 7/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
| ▸ | GABRE | P78334 | 1/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501290 | 0.85 | ALDH1A1 (0.43) | CYP4F2CYP4A11LMNATP53GABRP | |
| SCHEMBL15746649 | 0.85 | MRGPRX4 (0.51) | CYP4F2CYP4A11LMNATP53GABRP | |
| SCHEMBL7083009 | 0.83 | PARP1 (0.49) | LMNAGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4310539 | 0.81 | CYP4F2 (0.46) | CYP4F2CYP4A11OPRM1CSF1RMMP12 | |
| SCHEMBL2677778 | 0.81 | SMYD3 (0.54) | CYP4F2CYP4A11OPRM1GABRPGABRD | |
| SCHEMBL13945542 | 0.81 | PARP1 (0.48) | CSF1RLOXL2 | |
| SCHEMBL2176535 | 0.79 | LOXL2 (0.56) | CYP4F2CYP4A11GABRPGABRDGABRA1 | |
| SCHEMBL30193091 | 0.79 | RECQL (0.50) | CYP4F2CYP4A11GABRPGABRDGABRA1 | |
| SCHEMBL20377228 | 0.79 | CYP4F2 (0.45) | CYP4F2CYP4A11CSF1RGABRPGABRD | |
| SCHEMBL2328151 | 0.79 | RECQL (0.50) | CYP4F2CYP4A11GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111886219-B | Immunosuppressant, preparation method and pharmaceutical application thereof | 上海和誉生物医药科技有限公司 | 2023-04-25 | — | — | CN | disclosed |