Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22374246 | 0.88 | CDC25B (0.50) | PKMELANELMNAL3MBTL1TSHR | |
| SCHEMBL25845031 | 0.84 | PKM (0.38) | PKMELANELMNAL3MBTL1TSHR | |
| SCHEMBL28298353 | 0.80 | PKM (0.62) | PKMELANELMNAL3MBTL1TSHR | |
| SCHEMBL16005349 | 0.79 | ELANE (0.54) | ELANELMNAHPGDSHSD17B10ALDH1A1 | |
| SCHEMBL15447048 | 0.79 | LMNA (0.45) | PKMELANELMNAL3MBTL1TSHR | |
| SCHEMBL18785662 | 0.78 | ELANE (0.53) | ELANEHSD17B10GAAESR1ESR2 | |
| SCHEMBL22555047 | 0.77 | IDO1 (0.53) | PKMELANELMNATSHRNPC1 | |
| SCHEMBL30064961 | 0.77 | IDO1 (0.53) | PKMELANELMNATSHRNPC1 | |
| SCHEMBL21562113 | 0.76 | KDM4E (0.36) | PKMELANEL3MBTL1HSD17B10ALDH1A1 | |
| SCHEMBL1595502 | 0.76 | ELANE (0.46) | ELANEL3MBTL1TSHRHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230383421-A1 | METALLOPOLYMERS FOR CATALYTIC GENERATION OF HYDROGEN | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-11-30 | — | — | US | disclosed |
| US-11649548-B2 | Metallopolymers for catalytic generation of hydrogen | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-05-16 | — | — | US | disclosed |