Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 12/20 | 0.59 |
| ▸ | TCF4 | P15884 | 1/20 | 0.54 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.54 |
| ▸ | KIF11 | P52732 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19994736 | 1.00 | AURKA (0.59) | AURKATCF4CTNNB1KIF11MAPT | |
| SCHEMBL13836671 | 0.87 | TCF4 (0.64) | AURKATCF4CTNNB1KIF11MAPT | |
| SCHEMBL19994448 | 0.83 | ALDH1A1 (0.59) | MAPTKDM4ENPC1GUSBRAB9A | |
| SCHEMBL13974405 | 0.82 | TCF4 (0.70) | AURKATCF4CTNNB1KIF11MAPT | |
| SCHEMBL31005274 | 0.80 | TCF4 (0.59) | AURKATCF4CTNNB1KIF11MAPT | |
| SCHEMBL17370980 | 0.80 | TCF4 (0.59) | AURKATCF4CTNNB1KIF11MAPT | |
| SCHEMBL31005272 | 0.80 | TCF4 (0.59) | AURKATCF4CTNNB1KIF11MAPT | |
| SCHEMBL2554510 | 0.80 | NPC1 (0.58) | AURKAMAPTKDM4ENPC1GUSB | |
| SCHEMBL1663529 | 0.79 | TCF4 (0.58) | AURKATCF4CTNNB1KIF11MAPT | |
| SCHEMBL29506637 | 0.79 | TCF4 (0.79) | AURKATCF4CTNNB1KIF11MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234640-B | Benzimidazole derivatives as anticancer agents | 利昂贝拉尔中心 | 2023-04-07 | — | — | CN | disclosed |