Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8248926 | 0.92 | KMT2A (0.49) | KMT2AL3MBTL1CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL16136133 | 0.89 | KMT2A (0.46) | KMT2AL3MBTL1CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL19543673 | 0.82 | KMT2A (0.43) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL16311208 | 0.82 | KMT2A (0.43) | KMT2AL3MBTL1CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL2423783 | 0.80 | PDGFRB (0.41) | KMT2AL3MBTL1CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL16103839 | 0.78 | OPRM1 (0.44) | KMT2AL3MBTL1CYP11B2CYP11B1ALDH1A1 | |
| SCHEMBL23034762 | 0.78 | PTGS2 (0.40) | KMT2ACYP11B2CYP11B1ALDH1A1KDM4E | |
| SCHEMBL15792586 | 0.77 | SMN1; SMN2 (0.41) | KMT2AL3MBTL1ALDH1A1KDM4EHPGD | |
| SCHEMBL27746345 | 0.77 | NR1H2 (0.46) | KMT2AALDH1A1MTNR1AMTNR1BOPRM1 | |
| SCHEMBL16136136 | 0.76 | GPR119 (0.50) | KMT2AKDM4EOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023064493-A1 | COMPOUNDS AND METHODS FOR TREATING CORONAVIRUSES | Clear Creek Bio, Inc. (US) | 2023-04-20 | — | — | WO | disclosed |