Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | VNN1 | O95497 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7371232 | 0.81 | MGAM (0.76) | MGAMALDH1A1PDE4DNPC1RAB9A | |
| Bromide SCHEMBL7374451 | 0.80 | MGAM (0.73) | MGAMALDH1A1PDE4DNPC1RAB9A | |
| SCHEMBL4824941 | 0.78 | SRD5A2 (0.82) | SRD5A2SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL7816239 | 0.77 | SRD5A2 (0.81) | SRD5A2SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL28286128 | 0.76 | MGAM (0.78) | SRD5A2MGAMALDH1A1HPGDPDE4D | |
| SCHEMBL31629977 | 0.76 | MGAM (0.78) | SRD5A2MGAMALDH1A1HPGDPDE4D | |
| SCHEMBL20799509 | 0.75 | LMNA (0.50) | SRD5A2SMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL30875867 | 0.75 | RAB9A (0.62) | MGAMSMN1; SMN2ALDH1A1HPGDMAPT | |
| SCHEMBL29377331 | 0.73 | NPC1 (0.58) | SMN1; SMN2ALDH1A1HPGDMAPTKMT2A | |
| SCHEMBL18812959 | 0.72 | MGAM (0.58) | MGAMSMN1; SMN2ALDH1A1MAPTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416146-A1 | SUBSTITUTED 1H-PYRAZOLO [4,3-C] QUINOLINES, METHODS OF PREPARATION, AND USE THEREOF | Lomond Therapeutics, Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064133-A1 | SUBSTITUTED 1H-PYRAZOLO [4,3-c] QUINOLINES, METHODS OF PREPARATION, AND USE THEREOF | LOMOND THERAPEUTICS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |