SCHEMBL303476

SCHEMBL303476

NCc1cccc(CNCC(O)CNCc2cccc(CN)c2)c1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
BCHE P06276 8/20 0.47
BACE1 P56817 1/20 0.47
ADRB2 P07550 1/20 0.46
ENPP2 Q13822 1/20 0.46
ANPEP P15144 1/20 0.45
ERAP2 Q6P179 1/20 0.45
DNM1 Q05193 4/20 0.45
LMNA P02545 1/20 0.44
PNMT P11086 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8769305 0.93 ADRB2 (0.43) BCHEBACE1ADRB2ENPP2ANPEP
SCHEMBL16405824 0.92 BCHE (0.45) BCHEBACE1ADRB2ENPP2ANPEP
SCHEMBL23052827 0.92 ADRB2 (0.46) BCHEBACE1ADRB2ENPP2ANPEP
SCHEMBL29135337 0.89 ADRB2 (0.46) ADRB2ENPP2ANPEPERAP2DNM1
SCHEMBL1425602 0.86 ALDH1A1 (0.51) BCHEBACE1ADRB2ENPP2ANPEP
SCHEMBL834002 0.82 LOXL2 (0.52) BCHEENPP2PNMT
SCHEMBL30186883 0.82 LOXL2 (0.52) BCHEENPP2PNMT
SCHEMBL21799981 0.82 CA2 (0.47) BCHEADRB2ENPP2ANPEPERAP2
SCHEMBL13333688 0.80 BCHE (0.46) BCHEBACE1ADRB2DNM1LMNA
SCHEMBL21799668 0.79 ANPEP (0.40) BCHEADRB2ENPP2ANPEPERAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2822985-B1 AMINE CURABLE EPOXY RESIN COMPOSITION CONSTR RES & TECH GMBH (DE) 2016-11-30 EP claimed
US-20150025178-A1 AMINE CURABLE EPOXY RESIN COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2015-01-22 US claimed
EP-2822985-A1 AMINE CURABLE EPOXY RESIN COMPOSITION Construction Research & Technology GmbH (DE) 2015-01-14 EP claimed
WO-2013131776-A1 AMINE CURABLE EPOXY RESIN COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-09-12 WO claimed
US-20120205591-A1 SELF INDICATING RADIATION ALERT DOSIMETER PATEL GORDHABHAI N (US) 2012-08-16 US claimed
JP-4852410-B2 2012-01-11 JP claimed
US-7476874-B2 Self indicating radiation alert dosimeter JP LABORATORIES, INC. (US) 2009-01-13 US claimed
US-20060145091-A1 Self indicating radiation alert dosimeter JP LABORATORIES INC. 2006-07-06 US claimed
EP-1599744-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES, INC. (US) 2005-11-30 EP claimed
WO-2004077097-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES INC. (US) 2004-09-10 WO claimed
US-4605765-A HARDENERS FOR EPOXIDES; POLYAMIDES; FLEXIBILITY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1986-08-12 US claimed
EP-0088623-B1 POLYAMINE COMPOUND OF M-XYLENEDIAMINE AND ITS USE AS HARDENING AGENT MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-01-23 EP claimed
EP-0088623-A1 Polyamine compound of M-xylenediamine and its use as hardening agent MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-09-14 EP claimed
US-20170023681-A1 PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER NEW YORK UNIVERSITY 2017-01-26 US disclosed
EP-2822985-B1 AMINE CURABLE EPOXY RESIN COMPOSITION CONSTR RES & TECH GMBH (DE) 2016-11-30 EP disclosed
US-9086489-B2 Personal and area self-indicating instant radiation alert dosimeter JP LABORATORIES, INC (US) 2015-07-21 US disclosed
US-4605765-A HARDENERS FOR EPOXIDES; POLYAMIDES; FLEXIBILITY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1986-08-12 US disclosed
EP-0088623-B1 POLYAMINE COMPOUND OF M-XYLENEDIAMINE AND ITS USE AS HARDENING AGENT MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-01-23 EP disclosed
EP-0088623-A1 Polyamine compound of M-xylenediamine and its use as hardening agent MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-09-14 EP disclosed
EP-0088623-A1 Polyamine compound of M-xylenediamine and its use as hardening agent MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1983-09-14 EP disclosed