Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | STS | P08842 | 3/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4455357 | 0.87 | ACHE (0.47) | LMNACYP3A4SIGMAR1ALDH1A1ESR1 | |
| Sulfuric Acid SCHEMBL28036340 | 0.81 | ALDH1A1 (0.47) | LMNACYP3A4SIGMAR1ALDH1A1ESR1 | |
| SCHEMBL3282864 | 0.77 | ALDH1A1 (0.40) | LMNACYP3A4SIGMAR1ALDH1A1ESR1 | |
| O-Xylene SCHEMBL6155104 | 0.77 | TSHR (0.62) | LMNACYP3A4ALDH1A1KDM4ETSHR | |
| O-Xylene SCHEMBL29725142 | 0.77 | TSHR (0.62) | LMNACYP3A4ALDH1A1KDM4ETSHR | |
| O-Xylene SCHEMBL28085642 | 0.77 | TSHR (0.62) | LMNACYP3A4ALDH1A1KDM4ETSHR | |
| SCHEMBL9822762 | 0.75 | C5AR1 (0.44) | LMNACYP3A4SIGMAR1ALDH1A1ESR1 | |
| SCHEMBL6249561 | 0.75 | ESR1 (0.41) | LMNACYP3A4SIGMAR1ALDH1A1ESR1 | |
| O-Xylene SCHEMBL6364677 | 0.74 | TSHR (0.59) | LMNACYP3A4ALDH1A1KDM4ETSHR | |
| O-Xylene SCHEMBL3381229 | 0.74 | TSHR (0.59) | LMNACYP3A4ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115919663-A | Hair dyeing essential oil and preparation method thereof | 广州市芊彩化妆品有限公司 | 2023-04-07 | — | — | CN | claimed |