SCHEMBL4455357

SCHEMBL4455357

Cc1ccccc1N(N)N

nearest known ligand 0.52

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.47
TSHR P16473 1/20 0.47
SIGMAR1 Q99720 1/20 0.42
CYP3A4 P08684 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 3/20 0.40
ALDH1A1 P00352 3/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
ESR1 P03372 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 2/20 0.35
CYP2A6 P11509 2/20 0.35
CD44 P16070 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfuric Acid SCHEMBL30348917 0.87 LMNA (0.41) ACHETSHRSIGMAR1CYP3A4LMNA
SCHEMBL9461297 0.83 ACHE (0.47) ACHETSHRSIGMAR1CYP3A4TDP1
SCHEMBL3520282 0.81 SIGMAR1 (0.46) ACHETSHRSIGMAR1CYP3A4TDP1
Hydrochloric Acid SCHEMBL11560306 0.79 SIGMAR1 (0.44) ACHETSHRSIGMAR1CYP3A4TDP1
SCHEMBL9751387 0.79 TRPA1 (0.42) ACHETSHRCYP3A4TDP1LMNA
SCHEMBL7932525 0.79 ACHE (0.43) ACHETSHRSIGMAR1CYP3A4TDP1
SCHEMBL29193912 0.78 SMN1; SMN2 (0.35) TSHRCYP3A4TDP1ALDH1A1CA1
SCHEMBL29521738 0.77 TSHR (0.53) ACHETSHRSIGMAR1CYP3A4TDP1
SCHEMBL516435 0.77 TSHR (0.53) ACHETSHRSIGMAR1CYP3A4TDP1
SCHEMBL23505092 0.75 TSHR (0.39) ACHETSHRSIGMAR1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090149314-A1 MIXED OXIDE CATALYSTS BASF SE (DE) 2009-06-11 US disclosed