SCHEMBL30349477 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	ALDH1A1	P00352	2/20	0.40

▸	LMNA	P02545	1/20	0.40

▸	IAPP	P10997	1/20	0.39

▸	PTGER4	P35408	1/20	0.32

▸	PTGER3	P43115	1/20	0.32

▸	PTGER2	P43116	1/20	0.32

▸	HTR5A	P47898	1/20	0.31

▸	MAPT	P10636	1/20	0.31

▸	SMN1; SMN2	Q16637	2/20	0.31

▸	GAA	P10253	1/20	0.31

▸	HTT	P42858	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30349330	1.00	ALDH1A1 (0.40)	ALDH1A1LMNAIAPPPTGER4PTGER3
SCHEMBL8938495	0.80	HTR5A (0.32)	HTR5A
SCHEMBL9692553	0.77	TAAR1 (0.38)	HTR5A
SCHEMBL8938192	0.77	HTR5A (0.32)	HTR5A
SCHEMBL3771929	0.77	HTR5A (0.33)	HTR5A
SCHEMBL9691832	0.77	HTR5A (0.33)	HTR5A
SCHEMBL9692481	0.76	TAAR1 (0.39)	—
SCHEMBL8553459	0.75	SMN1; SMN2 (0.35)	ALDH1A1LMNAHTR5AMAPTSMN1; SMN2
SCHEMBL6794782	0.75	ADRA1A (0.42)	HTR5A
SCHEMBL10402771	0.74	HTR5A (0.33)	HTR5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023051793-A1	COMPOUND AS INHIBITOR OF COMPLEMENT FACTOR D, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF	武汉朗来科技发展有限公司	2023-04-06	—	—	WO	disclosed