SCHEMBL46585

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2331170	0.87	ALDH1A1 (0.50)	CA2CA1MAPTLMNAALDH1A1
	SCHEMBL23583038	0.86	ATR (0.41)	MTNR1AMTNR1BATRMAPTLMNA
	SCHEMBL3452984	0.84	ALDH1A1 (0.43)	MTNR1AMTNR1BCA2CA1MAPT
	SCHEMBL18799218	0.83	MTNR1A (0.46)	MTNR1AMTNR1BCA2CA1MAPT
	SCHEMBL14943783	0.83	LMNA (0.41)	CA2CA1MAPTLMNAALDH1A1
	SCHEMBL1830458	0.81	TSHR (0.57)	ATRCA2CA1LMNAHPGD
	SCHEMBL46614	0.81	CA2 (0.56)	CA2MAPTLMNAALDH1A1HPGD
	SCHEMBL26104374	0.81	MTNR1A (0.55)	MTNR1AMTNR1BMAPTLMNAALDH1A1
	SCHEMBL31135553	0.81	MTNR1A (0.55)	MTNR1AMTNR1BMAPTLMNAALDH1A1
	SCHEMBL26091012	0.80	CA2 (0.46)	MTNR1AMTNR1BCA2CA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.