Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.53 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 7/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11956144 | 0.94 | MAPT (0.56) | L3MBTL1MAPTRAB9AATML3MBTL4 | |
| SCHEMBL5844334 | 0.92 | MAPT (0.55) | L3MBTL1MAPTRAB9AATML3MBTL4 | |
| SCHEMBL12267206 | 0.92 | MAPT (0.55) | L3MBTL1MAPTRAB9AATML3MBTL4 | |
| SCHEMBL14279018 | 0.92 | MAPT (0.55) | L3MBTL1MAPTRAB9AATML3MBTL4 | |
| SCHEMBL11963361 | 0.90 | ACHE (0.61) | L3MBTL1MAPTRAB9AL3MBTL4L3MBTL3 | |
| SCHEMBL11890493 | 0.90 | L3MBTL4 (0.66) | L3MBTL1MAPTRAB9AL3MBTL4L3MBTL3 | |
| SCHEMBL3032513 | 0.89 | MAPT (0.54) | L3MBTL1MAPTRAB9AATML3MBTL4 | |
| SCHEMBL12967963 | 0.86 | L3MBTL1 (0.69) | L3MBTL1MAPTRAB9AATMHPGD | |
| SCHEMBL12428 | 0.86 | SMN1; SMN2 (0.54) | L3MBTL1MAPTRAB9AATMHPGD | |
| SCHEMBL10241943 | 0.86 | TSHR (0.64) | L3MBTL1MAPTRAB9AATMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298042-A1 | VMAT INHIBITORY COMPOUNDS | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-10-19 | — | — | US | disclosed |
| US-9546151-B2 | VMAT inhibitory compounds | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2017-01-17 | — | — | US | disclosed |
| CN-102692819-B | Photosensitive polymer combination and liquid crystal board | 东京应化工业株式会社 | 2016-11-23 | — | — | CN | disclosed |
| US-20160031852-A1 | VMAT INHIBITORY COMPOUNDS | WILMINGTON TRUST (LONDON) LIMITED, AS SECURITY AGENT (GB) | 2016-02-04 | — | — | US | disclosed |
| CN-102981365-B | Copolymer, resin composition, spacer for display panel, planarization film, thermosetting protective film, microlens, and process for producing copolymer | TOKYO OHKA KOGYO CO LTD | 2014-12-17 | — | — | CN | disclosed |
| CN-102977259-B | Copolymer, resin composition, spacer for display panel, planarization film, thermosetting protective film, microlens, and process for producing copolymer | TOKYO OHKA KOGYO CO LTD | 2014-12-17 | — | — | CN | disclosed |
| US-8716491-B2 | Benzimidazolium dyes and their use as fluorescent chemosensors | NEW YORK UNIVERSITY (US) | 2014-05-06 | — | — | US | disclosed |
| CN-101903426-B | Copolymer, resin composition, spacer for display panel, planarizing film, thermosetting protective film, microlens, and method for producing copolymer | TOKYO OHKA KOGYO CO LTD | 2013-05-08 | — | — | CN | disclosed |
| US-8409783-B2 | Copolymer, resin composition, spacer for display panel, planarization film, thermosetting protective film, microlens, and process for producing copolymer | TOKYO OHKA KOGYO CO., LTD. (JP) | 2013-04-02 | — | — | US | disclosed |
| CN-102981365-A | Copolymer, resin composition, spacer for display panel, planarization film, thermosetting protective film, microlens, and process for producing copolymer | TOKYO OHKA KOGYO CO LTD | 2013-03-20 | — | — | CN | disclosed |
| CN-102692819-A | Photosensitive resin composite and liquid crystal board | TOKYO OHKA KOGYO CO LTD | 2012-09-26 | — | — | CN | disclosed |
| US-7872716-B2 | Optical compensation film, polarizing plate and liquid crystal display | FUJIFILM CORPORATION (JP) | 2011-01-18 | — | — | US | disclosed |
| CN-101903426-A | Copolymer, resin composition, spacer for display panel, planarizing film, thermosetting protective film, microlens, and method for producing copolymer | TOKYO OHKA KOGYO CO LTD | 2010-12-01 | — | — | CN | disclosed |
| US-20100209847-A1 | COPOLYMER, RESIN COMPOSITION, SPACER FOR DISPLAY PANEL, PLANARIZATION FILM, THERMOSETTING PROTECTIVE FILM, MICROLENS, AND PROCESS FOR PRODUCING COPOLYMER | TOKYO OHKA KOGYO CO., LTD. (JP) | 2010-08-19 | — | — | US | disclosed |
| EP-1751113-B1 | UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL MYERS SQUIBB CO (US) | 2010-03-10 | — | — | EP | disclosed |
| US-20080306286-A1 | Isolation, Purification and Synthesis of Procyanidin B2 and Uses Thereof | PROTAMED, INC. | 2008-12-11 | — | — | US | disclosed |
| US-20080192191-A1 | Optical Compensation Film, Polarizing Plate and Liquid Crystal Display | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |
| US-7388021-B2 | Urea antagonists of P2Y1 receptor useful in the treatment of thrombotic conditions | BRISTOL MYERS SQUIBB COMPANY (US) | 2008-06-17 | — | — | US | disclosed |
| US-20070002232-A1 | Optical compensation film, polarizing plate and liquid crystal display device | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
| US-20070002232-A1 | Optical compensation film, polarizing plate and liquid crystal display device | FUJI PHOTO FILM CO., LTD. (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170298042-A1 | VMAT INHIBITORY COMPOUNDS | SLC18A2, SLC18A3, SLC6A2 | L3MBTL1 3462/4885MAPT 259/4885RAB9A 896/4885 |
| US-20160031852-A1 | VMAT INHIBITORY COMPOUNDS | SLC18A2, SLC18A3, SLC6A2 | L3MBTL1 3462/4885MAPT 259/4885RAB9A 896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.