SCHEMBL5844334

SCHEMBL5844334

CCCCCCOc1ccc(C)cc1OCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.55
ALDH1A1 P00352 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
GAA P10253 1/20 0.55
THRB P10828 1/20 0.55
L3MBTL4 Q8NA19 1/20 0.54
L3MBTL3 Q96JM7 1/20 0.54
L3MBTL1 Q9Y468 8/20 0.53
RAB9A P51151 3/20 0.53
ATM Q13315 1/20 0.53
HPGD P15428 5/20 0.49
TDP1 Q9NUW8 2/20 0.49
CYP2C9 P11712 3/20 0.49
CYP2C19 P33261 3/20 0.49
POLB P06746 2/20 0.49
MEN1 O00255 1/20 0.49
USP2 O75604 1/20 0.49
ALOX12 P18054 1/20 0.49
MAPK1 P28482 1/20 0.49
KMT2A Q03164 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12267206 1.00 MAPT (0.55) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL14279018 1.00 MAPT (0.55) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL11956144 0.98 MAPT (0.56) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL3034982 0.92 L3MBTL1 (0.56) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL13933171 0.92 MAPT (0.50) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL13933167 0.92 MAPT (0.50) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL11326840 0.91 L3MBTL4 (0.67) MAPTALDH1A1NPSR1THRBL3MBTL4
SCHEMBL18057105 0.90 MAPT (0.51) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL18057107 0.87 MAPT (0.49) MAPTALDH1A1NPSR1GAATHRB
SCHEMBL12431879 0.87 MAPT (0.65) MAPTALDH1A1NPSR1GAATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7615289-B2 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK ENERGY CO., LTD. (KR) 2009-11-10 US disclosed
US-7615289-B2 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK ENERGY CO., LTD. (KR) 2009-11-10 US disclosed
US-20080090779-A1 ANTIALLERGIC AGENTS INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2008-04-17 US disclosed
US-20080090779-A1 ANTIALLERGIC AGENTS INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2008-04-17 US disclosed
US-20070185059-A1 Antiallergic agents INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-08-09 US disclosed
US-20070185059-A1 Antiallergic agents INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-08-09 US disclosed
US-20070185110-A1 Antiallergic agents INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-08-09 US disclosed
US-20070185110-A1 Antiallergic agents INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-08-09 US disclosed
US-20070093643-A1 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK CORPORATION (KR) 2007-04-26 US disclosed
US-20070093643-A1 Organic electroluminescent polymer having 9,9-di(fluorenyl)-2,7-fluorenyl unit and organic electroluminescent device manufactured using the same SK CORPORATION (KR) 2007-04-26 US disclosed
US-20070042997-A1 Medicament for treatment of dermal pigmentation INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-02-22 US disclosed
US-20070042997-A1 Medicament for treatment of dermal pigmentation INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) 2007-02-22 US disclosed
US-7101651-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO.,LTD. (JP) 2006-09-05 US disclosed
US-20040166432-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-08-26 US disclosed
US-4272634-A Process for the production of intermediate oxidation products of toluenes having ether linkages DIRECTOR-GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1981-06-09 US disclosed
US-4220605-A LIQUID PHASE USING A SOLVENT OF LOW LOWER CARBOXYLIC ACID OR ANHYDRIDE, A SOLUBLE COBALT SALT AND BROMINE OR A BROMINE COMPOUND DIRECTOR GENERAL OF AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1980-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080090779-A1 ANTIALLERGIC AGENTS NAT1, EPX, HRH2 MAPT 2536/4885ALDH1A1 364/4885NPSR1 237/4885
US-20070185110-A1 Antiallergic agents NAT1, EPX, AHR MAPT 2469/4885ALDH1A1 340/4885NPSR1 243/4885
US-20070185059-A1 Antiallergic agents NAT1, EPX, AHR MAPT 2415/4885ALDH1A1 362/4885NPSR1 277/4885
US-20070042997-A1 Medicament for treatment of dermal pigmentation TYR, XDH, XPA MAPT 3082/4885ALDH1A1 140/4885NPSR1 2012/4885
US-20040166432-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process VEGFA, POLL, PIM3 MAPT 3581/4885ALDH1A1 2609/4885NPSR1 2305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.