SCHEMBL30350353

SCHEMBL30350353

Clc1cccc(-c2cc(Cl)cc(Br)c2Br)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDO2 P48775 1/20 0.41
ALOX5 P09917 1/20 0.40
DHFR P00374 1/20 0.40
TAAR1 Q96RJ0 1/20 0.39
NUDT1 P36639 2/20 0.37
KMT2A Q03164 2/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
MEN1 O00255 1/20 0.37
GAA P10253 1/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NOTUM Q6P988 2/20 0.37
ESR2 Q92731 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
NFKB1 P19838 1/20 0.37
NFKB2 Q00653 1/20 0.37
RELA Q04206 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20687339 0.80 TDO2 (0.43) TDO2ALOX5DHFRTAAR1NUDT1
SCHEMBL19163762 0.80 TDO2 (0.43) TDO2ALOX5DHFRTAAR1NUDT1
SCHEMBL14907136 0.79 TDO2 (0.46) TDO2ALOX5DHFRTAAR1NUDT1
SCHEMBL3561173 0.76 ALDH1A1 (0.58) TDO2ALOX5DHFRTAAR1NUDT1
SCHEMBL27353355 0.73 CNR1 (0.41) ESR2
SCHEMBL5947991 0.73 GABRP (0.41) TDO2ALOX5TAAR1KMT2AMEN1
SCHEMBL25368058 0.73 ALDH1A1 (0.46) ALOX5KMT2AMEN1SMN1; SMN2TSHR
SCHEMBL4452357 0.72 AHR (0.45) TDO2ALOX5DHFRTAAR1NUDT1
SCHEMBL9862849 0.72 NPC1 (0.50) TDO2ALOX5DHFRTAAR1NUDT1
SCHEMBL24929014 0.72 TDO2 (0.40) TDO2ALOX5DHFRTAAR1NUDT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3460863-B1 COMPOUND INCLUDING NITROGEN AND ORGANIC ELECTROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2024-04-24 EP disclosed
CN-109516992-B Nitrogen-containing compound and organic electroluminescent device comprising same 三星显示有限公司 2023-04-07 CN disclosed