Sugi Predict

Sugi Predict / Compounds / SCHEMBL3561173

SCHEMBL3561173

SCHEMBL3561173

Clc1cccc(-c2ccccc2Br)c1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.58
▸ MAPK1 P28482 1/20 0.58
▸ TDO2 P48775 1/20 0.43
▸ NPC1 O15118 3/20 0.43
▸ RAB9A P51151 2/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ TP53 P04637 1/20 0.43
▸ TSHR P16473 1/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43
▸ RELA Q04206 1/20 0.43
▸ KMT2A Q03164 3/20 0.42
▸ MEN1 O00255 2/20 0.42
▸ ADORA2A P29274 1/20 0.42
▸ ADORA1 P30542 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ MAOB P27338 1/20 0.42
▸ ALOX5 P09917 1/20 0.42
▸ DHFR P00374 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862849 0.84 NPC1 (0.50) ALDH1A1TDO2NPC1RAB9ASMN1; SMN2
SCHEMBL17709510 0.84 ALDH1A1 (0.71) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL20687339 0.83 TDO2 (0.43) TDO2NPC1RAB9ASMN1; SMN2TP53
SCHEMBL19163762 0.83 TDO2 (0.43) TDO2NPC1RAB9ASMN1; SMN2TP53
SCHEMBL23487149 0.83 MAPK1 (0.56) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL4230820 0.83 MAPK1 (0.56) ALDH1A1MAPK1NPC1RAB9ASMN1; SMN2
SCHEMBL14907136 0.83 TDO2 (0.46) TDO2NPC1RAB9ASMN1; SMN2TP53
SCHEMBL30140981 0.82 TDO2 (0.40) ALDH1A1MAPK1TDO2NPC1RAB9A
SCHEMBL24929014 0.82 TDO2 (0.40) ALDH1A1MAPK1TDO2NPC1RAB9A
SCHEMBL29536497 0.82 TDO2 (0.47) ALDH1A1TDO2NPC1RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112521361-A Spiro [ fluorene-9, 9' -xanthene ] compound and preparation method thereof 河南省科学院化学研究所有限公司 2021-03-19 — — CN claimed
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE ATRANSEN PHARMA LTD (JP) 2026-02-05 — — US disclosed
WO-2025121854-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2025-06-12 — — WO disclosed
EP-4501906-A1 TETRAHYDRONAPHTHALENE DERIVATIVE Atransen Pharma Ltd. (JP) 2025-02-05 — — EP disclosed
CN-118974007-A Tetrahydronaphthalene derivatives 阿创森制药股份有限公司 2024-11-15 — — CN disclosed
EP-4451832-A2 HETEROAROMATIC COMPOUNDS Merck Patent GmbH (DE) 2024-10-23 — — EP disclosed
EP-3728275-B1 HETEROAROMATIC COMPOUNDS MERCK PATENT GMBH (DE) 2024-09-04 — — EP disclosed
US-20240147853-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2024-05-02 — — US disclosed
CN-113937231-B Organic electroluminescent device and electronic device 陕西莱特迈思光电材料有限公司 2024-03-19 — — CN disclosed
US-20240059714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-02-22 — — US disclosed
US-20140326979-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SUMITOMO CHEMICAL CO., LTD (JP) 2014-11-06 — — US disclosed
US-20140231713-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SUMITOMO CHEMICAL CO., LTD (JP) 2014-08-21 — — US disclosed
US-20140231713-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SUMITOMO CHEMICAL CO., LTD (JP) 2014-08-21 — — US disclosed
WO-2013045410-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SOLVAY SA (BE) 2013-04-04 — — WO disclosed
WO-2013045411-A1 SPIROBIFLUORENE COMPOUNDS FOR LIGHT EMITTING DEVICES SOLVAY SA (BE) 2013-04-04 — — WO disclosed
WO-2012048819-A1 NOVEL SPIROBIFLUORENE COMPOUNDS SOLVAY (SOCIETE ANONYME) (BE) 2012-04-19 — — WO disclosed
US-7858624-B2 Piperidine and morpholine renin inhibitors VITAE PHARMACEUTICALS, INC. (US) 2010-12-28 — — US disclosed
US-20090275581-A1 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. 2009-11-05 — — US disclosed
US-20090264428-A1 Renin Inhibitors VITAE PHARMACEUTICALS, INC. 2009-10-22 — — US disclosed
US-20090264432-A1 Piperidine and Morpholine Renin Inhibitors VITAE PHARMACEUTICALS, INC. 2009-10-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240059714-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES CNKSR1, LIFR, NPY2R ALDH1A1 1062/4885MAPK1 1169/4885TDO2 3308/4885
US-20090275581-A1 RENIN INHIBITORS REN, ACE, SERPINB1 ALDH1A1 1084/4885MAPK1 1494/4885TDO2 3696/4885
US-20090264432-A1 Piperidine and Morpholine Renin Inhibitors REN, ACE, PREP ALDH1A1 2168/4885MAPK1 1239/4885TDO2 4699/4885
US-20260035339-A1 TETRAHYDRONAPHTHALENE DERIVATIVE LATS1, LATS2, BCAT1 ALDH1A1 1267/4885MAPK1 152/4885TDO2 2858/4885
US-20240147853-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 ALDH1A1 10/4885MAPK1 304/4885TDO2 492/4885
US-20090264428-A1 Renin Inhibitors REN, ACE, SERPINB1 ALDH1A1 1060/4885MAPK1 2221/4885TDO2 3958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.