SCHEMBL30355253

SCHEMBL30355253

CN(C(=O)CO)c1c(I)c(C(N)=O)c(I)c(C(=O)N(CC(O)CO)CC(O)CO)c1I

nearest known ligand 0.39

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.39
HIF1A Q16665 1/20 0.39
LMNA P02545 2/20 0.37
TYMP P19971 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7095050 1.00 CYP2C19 (0.39) CYP2C19HIF1ALMNATYMP
SCHEMBL9735219 0.89 LMNA (0.32) CYP2C19HIF1ALMNA
SCHEMBL9736246 0.86 CYP2C19 (0.45) CYP2C19HIF1ALMNA
SCHEMBL8380649 0.84 CYP2C19 (0.41) CYP2C19HIF1ALMNA
SCHEMBL28198605 0.84 CYP2C19 (0.35) CYP2C19HIF1ALMNA
SCHEMBL27965331 0.83 CYP2C19 (0.37) CYP2C19HIF1ALMNA
SCHEMBL9190900 0.83 LMNA (0.33) CYP2C19HIF1ALMNA
SCHEMBL29234146 0.82 LMNA (0.30) CYP2C19HIF1ALMNA
SCHEMBL1856683 0.81 CYP2C19 (0.60) CYP2C19HIF1ALMNA
SCHEMBL9287744 0.81 CYP2C19 (0.42) CYP2C19HIF1ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240271295-A1 ELECTROCHEMICAL IODINATION OF N,N'-(2,3-DIHYDROXYPROPYL)-5-HYDROXY-1,3-BENZENEDICARBOXAMIDE BRACCO IMAGING S.P.A. (IT) 2024-08-15 US claimed
EP-4405329-B1 ELECTROCHEMICAL IODINATION OF N,N'-(2,3-DIHYDROXYPROPYL)-5-HYDROXY-1,3-BENZENEDICARBOXAMIDE BRACCO IMAGING SPA (IT) 2025-08-20 EP disclosed
EP-4405329-A1 ELECTROCHEMICAL IODINATION OF N,N'-(2,3-DIHYDROXYPROPYL)-5-HYDROXY-1,3-BENZENEDICARBOXAMIDE Bracco Imaging SPA (IT) 2024-07-31 EP disclosed
WO-2023046815-A1 ELECTROCHEMICAL IODINATION OF N,N'-(2,3-DIHYDROXYPROPYL)-5-HYDROXY-1,3-BENZENEDICARBOXAMIDE BRACCO IMAGING SPA (IT) 2023-03-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240271295-A1 ELECTROCHEMICAL IODINATION OF N,N'-(2,3-DIHYDROXYPROPYL)-5-HYDROXY-1,3-BENZENEDICARBOXAMIDE HAO2, HDHD5, TPO CYP2C19 526/4885HIF1A 400/4885LMNA 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.