Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.59 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.59 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 12/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.58 |
| ▸ | GAA | P10253 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | GLA | P06280 | 5/20 | 0.58 |
| ▸ | GFER | P55789 | 3/20 | 0.58 |
| ▸ | RECQL | P46063 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | BLM | P54132 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035648 | 0.84 | MAPKAPK2 (0.49) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL725354 | 0.79 | PLAU (0.66) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL9578438 | 0.79 | PLAU (0.46) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL28151598 | 0.79 | PLAU (0.66) | MAPTKDM4EGAAALDH1A1GFER | |
| Hydrochloric Acid SCHEMBL6621844 | 0.78 | PLAU (0.63) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL20485660 | 0.77 | MEN1 (0.65) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL1925827 | 0.76 | MAPT (0.76) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL172884 | 0.76 | MEN1 (0.59) | MEN1KMT2ARXFP1CACNA1BAPBA1 | |
| SCHEMBL8873645 | 0.76 | ALDH1A1 (0.56) | MAPTKDM4EALDH1A1RAB9AGLA | |
| SCHEMBL1663312 | 0.76 | MAPT (0.60) | MEN1KMT2ARXFP1CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170020900-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | NIH - DEITR | 2017-01-26 | — | — | US | disclosed |
| US-9301940-B2 | Methods for screening antimicrobial and antiviral compounds and uses thereof | THE GENERAL HOSPITAL CORPORATION (US) | 2016-04-05 | — | — | US | disclosed |
| US-20100216852-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION | 2010-08-26 | — | — | US | disclosed |
| WO-2008066576-A2 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | THE GENERAL HOSPITAL CORPORATION (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170020900-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | ZC3HAV1, MAVS, EIF2AK2 | MEN1 4593/4885KMT2A 3636/4885RXFP1 4370/4885 |
| US-20100216852-A1 | METHODS FOR SCREENING ANTIMICROBIAL AND ANTIVIRAL COMPOUNDS AND USES THEREOF | ZC3HAV1, MAVS, EIF2AK2 | MEN1 4593/4885KMT2A 3636/4885RXFP1 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.