SCHEMBL725354

SCHEMBL725354

Nc1ccc2nc(N)[nH]c2c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.66
HTR3E A5X5Y0 1/20 0.66
HTR3B O95264 1/20 0.66
HTR3A P46098 1/20 0.66
BACE1 P56817 1/20 0.66
HTR3D Q70Z44 1/20 0.66
HTR3C Q8WXA8 1/20 0.66
MEN1 O00255 8/20 0.63
KMT2A Q03164 8/20 0.63
RXFP1 Q9HBX9 2/20 0.63
CACNA1B Q00975 1/20 0.63
APBA1 Q02410 1/20 0.63
MAPT P10636 8/20 0.61
KDM4E B2RXH2 7/20 0.61
ALDH1A1 P00352 6/20 0.61
GAA P10253 5/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
GLA P06280 3/20 0.61
NPC1 O15118 3/20 0.61
RAB9A P51151 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6621844 0.98 PLAU (0.63) PLAUHTR3EHTR3BHTR3ABACE1
SCHEMBL29449363 0.83 MEN1 (0.57) PLAUHTR3EHTR3BHTR3ABACE1
SCHEMBL118057 0.83 MEN1 (0.57) PLAUHTR3EHTR3BHTR3ABACE1
Hydrochloric Acid SCHEMBL6621838 0.81 MEN1 (0.55) PLAUHTR3EHTR3BHTR3ABACE1
SCHEMBL28241210 0.80 PLAU (0.57) PLAUHTR3EHTR3BHTR3ABACE1
SCHEMBL3035650 0.79 MEN1 (0.59) PLAUMEN1KMT2ARXFP1CACNA1B
SCHEMBL30147103 0.79 MEN1 (0.59) MEN1KMT2ARXFP1CACNA1BAPBA1
SCHEMBL1925827 0.79 MAPT (0.76) MEN1KMT2ARXFP1CACNA1BAPBA1
SCHEMBL172884 0.79 MEN1 (0.59) MEN1KMT2ARXFP1CACNA1BAPBA1
SCHEMBL1663312 0.79 MAPT (0.60) HTR3EHTR3BHTR3ABACE1HTR3D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109709-A1 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS MIRATI THERAPEUTICS INC (US) 2026-04-23 US claimed
WO-2025085329-A1 MULTIFUNCTIONAL ADHESION PROMOTER FOR SEMICONDUCTOR DEVICE PACKAGES WOLFSPEED, INC. (US) 2025-04-24 WO claimed
US-20250122413-A1 Multifunctional Adhesion Promoter for Semiconductor Device Packages U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2025-04-17 US claimed
CN-114976047-B Catalyst for electro-oxidation of methanol and preparation method thereof 南京大学 2024-08-23 CN claimed
CN-114976047-A Catalyst for methanol electrooxidation and preparation method thereof 南京大学 2022-08-30 CN claimed
CN-112426884-A Antibacterial composite reverse osmosis membrane and preparation method thereof 嘉兴市爵拓科技有限公司 2021-03-02 CN claimed
EP-3105210-A1 BENZIMIDAZOL-2-AMINES AS MIDH1 INHIBITORS Bayer Pharma Aktiengesellschaft (DE) 2016-12-21 EP claimed
WO-2015121209-A1 BENZIMIDAZOL-2-AMINES AS MIDH1 INHIBITORS BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2015-08-20 WO claimed
EP-1576093-A4 3-DEOXYGLUCOSONE AND SKIN DYNAMIS THERAPEUTICS INC (US) 2009-07-08 EP claimed
US-20070065443-A1 Fructoseamine 3 kinase and the formation of collagen and elastin DYNAMIS THERAPEUTICS, INC. 2007-03-22 US claimed
EP-1753861-A2 FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN Dynamis Therapeutics, Inc. (US) 2007-02-21 EP claimed
EP-1576093-A2 3-DEOXYGLUCOSONE AND SKIN Dynamis Therapeutics, Inc. (US) 2005-09-21 EP claimed
WO-2005079463-A2 FRUCTOSEAMINE 3 KINASE AND THE FORMATION OF COLLAGEN AND ELASTIN DYNAMIS THERAPEUTICS, INC. (US) 2005-09-01 WO claimed
US-20050159383-A1 Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) DYNAMIS THERAPEUTICS, INC. 2005-07-21 US claimed
WO-2005007083-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2005-01-27 WO claimed
US-20030219440-A1 3-deoxyglucosone and skin DYNAMIS THERAPEUTICS, INC. 2003-11-27 US claimed
WO-2003089601-A2 3-DEOXYGLUCOSONE AND SKIN DYNAMIS THERAPEUTICS, INC. (US) 2003-10-30 WO claimed
US-4321363-A Adsorbent for urokinase containing agarose NIPPON SODA COMPANY LIMITED (JP) 1982-03-23 US claimed
WO-2025085329-A1 MULTIFUNCTIONAL ADHESION PROMOTER FOR SEMICONDUCTOR DEVICE PACKAGES WOLFSPEED, INC. (US) 2025-04-24 WO disclosed
US-4321363-A Adsorbent for urokinase containing agarose NIPPON SODA COMPANY LIMITED (JP) 1982-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070065443-A1 Fructoseamine 3 kinase and the formation of collagen and elastin FN3K, PDXK, COLGALT1 PLAU 913/4885HTR3E 2038/4885HTR3B 1868/4885
US-20260109709-A1 2-AMINO IMIDAZOLE DERIVATIVES AS PRMT5 INHIBITORS PRMT5, PRMT1, PRMT3 PLAU 4162/4885HTR3E 3497/4885HTR3B 3914/4885
US-20030219440-A1 3-deoxyglucosone and skin DPM1, G6PD, UGGT1 PLAU 1729/4885HTR3E 3243/4885HTR3B 2453/4885
US-20050159383-A1 Administering enzyme inhibitors; wrinkling and aging resistance; prevents formation Advanced Glycation End Products (AGEs) AGER, GLA, GALE PLAU 1583/4885HTR3E 1522/4885HTR3B 2772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.