SCHEMBL1663312

SCHEMBL1663312

Nc1ccc2nc(Cl)[nH]c2c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.60
KDM4E B2RXH2 11/20 0.60
MEN1 O00255 10/20 0.60
KMT2A Q03164 10/20 0.60
GAA P10253 10/20 0.60
ALDH1A1 P00352 8/20 0.60
SMN1; SMN2 Q16637 7/20 0.60
NPC1 O15118 7/20 0.60
RAB9A P51151 7/20 0.60
HPGD P15428 6/20 0.60
TP53 P04637 4/20 0.60
NFKB1 P19838 2/20 0.60
HSD17B10 Q99714 2/20 0.60
APP P05067 1/20 0.60
SNCA P37840 1/20 0.60
NFKB2 Q00653 1/20 0.60
RELA Q04206 1/20 0.60
MCL1 Q07820 1/20 0.60
POLB P06746 6/20 0.59
TDP1 Q9NUW8 5/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1663309 0.84 MAPKAPK2 (0.49) MAPTKDM4EMEN1KMT2AGAA
SCHEMBL725354 0.79 PLAU (0.66) MAPTKDM4EMEN1KMT2AGAA
SCHEMBL1748354 0.79 ALDH1A1 (0.66) MAPTKDM4EMEN1KMT2AALDH1A1
Hydrochloric Acid SCHEMBL6621844 0.78 PLAU (0.63) MAPTKDM4EMEN1KMT2AGAA
SCHEMBL1925827 0.76 MAPT (0.76) MAPTKDM4EMEN1KMT2AGAA
SCHEMBL4376248 0.76 PLAU (0.61) KDM4EGAAALDH1A1HPGDPOLB
SCHEMBL172884 0.76 MEN1 (0.59) MAPTKDM4EMEN1KMT2AGAA
SCHEMBL482021 0.76 ALDH1A1 (0.56) MAPTKDM4EALDH1A1RAB9ALMNA
SCHEMBL1747975 0.76 ALPL (0.56) ALDH1A1HTR3EHTR3BHTR3ABACE1
SCHEMBL827359 0.76 KMT2A (0.58) MAPTKDM4EKMT2AGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2024-02-29 US disclosed
US-11786520-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIV ANA G MENDEZ INC (US) 2023-10-17 US disclosed
US-11311531-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIV ANA G MENDEZ INC (US) 2022-04-26 US disclosed
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2021-09-23 US disclosed
US-20200261441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2020-08-20 US disclosed
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2020-08-06 US disclosed
US-10624885-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIV ANA G MENDEZ INC (US) 2020-04-21 US disclosed
US-20180214441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition SISTEMA UNIVERSITARIO ANA G. MENDEZ, INC. (US) 2018-08-02 US disclosed
US-9622991-B2 Hematopoietic growth factor mimetic small molecule compounds and their uses LIGAND PHARMACEUTICALS INC. (US) 2017-04-18 US disclosed
CN-102656141-B Micromolecular compound of simulation hemopoieticgrowth factor and uses thereof LIGAND PHARMACEUTICALS INC. (US) 2016-04-06 CN disclosed
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-09-10 US disclosed
US-20140243324-A1 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS LIGAND PHARMACEUTICALS INCORPORATED (US) 2014-08-28 US disclosed
EP-2642994-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS Ligand Pharmaceuticals Incorporated (US) 2013-10-02 EP disclosed
CN-103282034-A Use of hematopoietic growth factor mimetics LIGAND PHARM INC 2013-09-04 CN disclosed
US-20120295904-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2012-11-22 US disclosed
EP-2488486-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES Ligand Pharmaceuticals Inc. (US) 2012-08-22 EP disclosed
WO-2012068406-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS LIGAND PHARMACEUTICALS INCORPORATED (US) 2012-05-24 WO disclosed
WO-2011046954-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2011-04-21 WO disclosed
US-5347008-A Thio(cyclo) alkanepolycarboxylic acids containing heterocyclic substituents CIBA-GEIGY CORPORATION (US) 1994-09-13 US disclosed
US-5152929-A Corrosion inhibitors for water systems CIBA-GEIGY CORPORATION (US) 1992-10-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11786520-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS MAPT 4399/4885KDM4E 2442/4885MEN1 4042/4885
US-20140243324-A1 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS HGF, EPOR, MPL MAPT 4622/4885KDM4E 3484/4885MEN1 1370/4885
US-11311531-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 MAPT 4449/4885KDM4E 2129/4885MEN1 4053/4885
US-20200246328-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 MAPT 4449/4885KDM4E 2129/4885MEN1 4053/4885
US-10624885-B2 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 MAPT 4449/4885KDM4E 2129/4885MEN1 4053/4885
US-20210290615-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS MAPT 4399/4885KDM4E 2442/4885MEN1 4042/4885
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES MPL, CSF3R, HGF MAPT 4411/4885KDM4E 1944/4885MEN1 1395/4885
US-20120295904-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES MPL, CSF3R, HGF MAPT 4411/4885KDM4E 1944/4885MEN1 1395/4885
US-20180214441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 MAPT 4449/4885KDM4E 2129/4885MEN1 4053/4885
US-20240066023-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition AHNAK, RECQL, NBAS MAPT 4399/4885KDM4E 2442/4885MEN1 4042/4885
US-20200261441-A1 Method for producing benzazoloquinolium (BQs) salts and using the biological activity of the composition RECQL, AHNAK, NDUFS1 MAPT 4449/4885KDM4E 2129/4885MEN1 4053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.