Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | MMP14 | P50281 | 1/20 | 0.47 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1028457 | 0.89 | CYP2C9 (0.50) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL30710226 | 0.87 | METAP2 (0.57) | SMN1; SMN2ALDH1A1MCL1CA12CA1 | |
| SCHEMBL26695126 | 0.87 | METAP2 (0.57) | SMN1; SMN2ALDH1A1MCL1CA12CA1 | |
| SCHEMBL2892466 | 0.86 | LMNA (0.50) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL18151742 | 0.81 | KMT2A (0.60) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| Ammonia Solution, Strong SCHEMBL18152538 | 0.80 | KMT2A (0.59) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL3512721 | 0.78 | CYP2C9 (0.52) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL1075767 | 0.77 | CACNA1B (0.49) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL3514343 | 0.77 | CYP2C9 (0.55) | LMNAHTTSMN1; SMN2TSHRKDM4E | |
| SCHEMBL1075764 | 0.76 | CACNA1B (0.47) | LMNAHTTSMN1; SMN2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | BIOLIPOX AB (SE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010029300-A1 | BIS AROMATIC COMPOUNDS FOR USE IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2010-03-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294853-A1 | Bis Aromatic Compounds for Use in the Treatment of Inflammation | LTC4S, LTB4R2, LTB4R | LMNA 699/4885HTT 3253/4885SMN1; SMN2 4690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.