Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 10/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.31 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | SPR | P35270 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358997 | 0.79 | KCNK3 (0.41) | KCNK3KCNK9TRPV4NAMPTCHRNA4 | |
| SCHEMBL30359148 | 0.75 | CHRNA4 (0.43) | KCNK3KCNK9TRPV4NAMPTCHRNA4 | |
| SCHEMBL30358999 | 0.70 | KCNK3 (0.42) | KCNK3KCNK9TRPV4NAMPTCHRNA4 | |
| SCHEMBL30359111 | 0.69 | HTR2A (0.41) | KCNK3KCNK9CHRNA4CHRNB2CHRNB4 | |
| SCHEMBL30359020 | 0.68 | TRPV4 (0.40) | KCNK3KCNK9TRPV4CHRNA4CHRNB2 | |
| SCHEMBL30359067 | 0.67 | KCNK3 (0.45) | KCNK3KCNK9TRPV4CHRNA4CHRNB2 | |
| SCHEMBL30359028 | 0.67 | TRPV4 (0.41) | TRPV4MGLLCHRNA4SPR | |
| SCHEMBL30359106 | 0.66 | KCNK3 (0.43) | KCNK3KCNK9TRPV4CHRNA4CHRNB2 | |
| SCHEMBL30359077 | 0.64 | ALDH1A1 (0.48) | MGLL | |
| SCHEMBL2302714 | 0.64 | CHRNB2 (0.45) | CHRNA4CHRNB2CHRNB4CHRNA3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |