Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358993 | 0.82 | TRPV4 (0.38) | TRPV4 | |
| SCHEMBL30359120 | 0.75 | TRPV4 (0.42) | TRPV4RAB9AALDH1A1NPC1SPR | |
| SCHEMBL30359020 | 0.75 | TRPV4 (0.40) | TRPV4RAB9AALDH1A1NPC1SPR | |
| SCHEMBL30359147 | 0.74 | ALDH1A1 (0.42) | TRPV4MGLLALDH1A1 | |
| SCHEMBL30268871 | 0.72 | SSTR4 (0.54) | SSTR4RAB9AALDH1A1NPC1HSD17B10 | |
| SCHEMBL30358999 | 0.71 | KCNK3 (0.42) | TRPV4SPRCHRNA4 | |
| SCHEMBL30359182 | 0.71 | KCNK3 (0.44) | TRPV4POLB | |
| SCHEMBL2725169 | 0.69 | HPGD (0.49) | RAB9AMGLLALDH1A1NPC1HSD17B10 | |
| SCHEMBL30359148 | 0.69 | CHRNA4 (0.43) | TRPV4RAB9ANPC1CHRNA4 | |
| SCHEMBL29663502 | 0.69 | MGLL (0.36) | SSTR4RAB9AMGLLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |