Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30358993 | 0.76 | TRPV4 (0.38) | GAATRPV4HTR2AIDH1 | |
| SCHEMBL30359085 | 0.76 | KCNK3 (0.44) | KCNK3KCNK9TRPV4IDH1 | |
| SCHEMBL30359028 | 0.71 | TRPV4 (0.41) | TRPV4POLB | |
| SCHEMBL23563560 | 0.71 | RORC (0.37) | KCNK3KCNK9KMT2AMEN1GFER | |
| SCHEMBL26702878 | 0.71 | KMT2A (0.54) | KMT2AMEN1GFERTLR7GAA | |
| SCHEMBL30359057 | 0.71 | KDM4E (0.42) | KCNK3KCNK9KMT2ATLR7TRPV4 | |
| SCHEMBL30359010 | 0.70 | SLC6A2 (0.46) | — | |
| SCHEMBL27830319 | 0.69 | TLR7 (0.54) | KMT2AMEN1GFERTLR7GAA | |
| SCHEMBL13466913 | 0.69 | KMT2A (0.53) | KMT2AMEN1GFERTLR7GAA | |
| SCHEMBL26703529 | 0.69 | HRH3 (0.55) | KMT2AMEN1GFERTLR7CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116057057-A | Conjugates of alpha 2-adrenoceptor subtype C (alpha-2C) antagonists and TASK1/3 channel blockers for the treatment of sleep apnea | 拜耳公司 | 2023-05-02 | — | — | CN | disclosed |