Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.31 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21998829 | 1.00 | EPAS1 (0.41) | EPAS1L3MBTL1ALDH1A1PKMMAPK1 | |
| SCHEMBL14524889 | 0.97 | EPAS1 (0.40) | EPAS1L3MBTL1ALDH1A1PKMMAPK1 | |
| SCHEMBL24966444 | 0.93 | L3MBTL1 (0.38) | EPAS1L3MBTL1ALDH1A1PKMMBTD1 | |
| SCHEMBL942322 | 0.93 | L3MBTL1 (0.38) | EPAS1L3MBTL1ALDH1A1PKMMBTD1 | |
| SCHEMBL5682444 | 0.93 | L3MBTL1 (0.38) | EPAS1L3MBTL1ALDH1A1PKMMAPK1 | |
| SCHEMBL3094274 | 0.90 | ALDH1A1 (0.39) | EPAS1L3MBTL1ALDH1A1PKMMAPK1 | |
| SCHEMBL18501167 | 0.90 | L3MBTL1 (0.36) | EPAS1L3MBTL1ALDH1A1PKMGRIN1 | |
| SCHEMBL29895427 | 0.90 | L3MBTL1 (0.36) | EPAS1L3MBTL1ALDH1A1PKMMAPK1 | |
| SCHEMBL10622966 | 0.90 | L3MBTL1 (0.36) | EPAS1L3MBTL1ALDH1A1PKMMAPK1 | |
| SCHEMBL18526481 | 0.90 | ALDH1A1 (0.39) | EPAS1L3MBTL1ALDH1A1PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11566032-B2 | Radio-protective and chemo-protective substituted thiols | Tonix Pharmaceuticals, Inc. (US) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11566032-B2 | Radio-protective and chemo-protective substituted thiols | MGMT, GSTP1, GSTA1 | EPAS1 1249/4885L3MBTL1 660/4885ALDH1A1 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.