Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7864574 | 1.00 | TRPV4 (0.39) | TRPV4KMT2AMEN1CA12CA1 | |
| SCHEMBL7865893 | 0.82 | NFE2L2 (0.41) | TRPV4KMT2AMEN1NFE2L2CCR4 | |
| SCHEMBL31525266 | 0.82 | CA2 (0.49) | KMT2AMEN1CA12CA1CA2 | |
| SCHEMBL7867589 | 0.82 | TRPV4 (0.42) | TRPV4KMT2ACA12CA1CA2 | |
| SCHEMBL31121359 | 0.77 | SLC22A12 (0.44) | TRPV4KMT2AMEN1NFE2L2CCR4 | |
| SCHEMBL31121360 | 0.77 | SLC22A12 (0.44) | TRPV4KMT2AMEN1NFE2L2CCR4 | |
| SCHEMBL4394771 | 0.77 | SLC22A12 (0.44) | TRPV4KMT2AMEN1NFE2L2CCR4 | |
| SCHEMBL30953866 | 0.75 | ESR1 (0.40) | TRPV4KMT2AMEN1CA1CA2 | |
| SCHEMBL1500874 | 0.72 | CA2 (0.46) | TRPV4KMT2AMEN1CA12CA1 | |
| SCHEMBL27849554 | 0.71 | MAPK1 (0.45) | KMT2AMEN1MAPK1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4698175-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITOR, COMBINATIONS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2026-02-25 | — | — | EP | disclosed |
| WO-2025136811-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | IDEAYA BIOSCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| WO-2024217563-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITOR, COMBINATIONS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-10-24 | — | — | WO | disclosed |
| EP-4433474-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2024-09-25 | — | — | EP | disclosed |
| CN-118556053-A | Lysine acetyl transferase 6A (KAT 6A) inhibitor and application thereof | 英矽智能科技知识产权有限公司 | 2024-08-27 | — | — | CN | disclosed |
| WO-2023088233-A1 | LYSINE ACETYLTRANSFERASE 6A (KAT6A) INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2023-05-25 | — | — | WO | disclosed |