SCHEMBL7865893

SCHEMBL7865893

COc1nccc(Cl)c1S(=O)(=O)Cl

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NFE2L2 Q16236 6/20 0.41
▸ CCR4 P51679 7/20 0.40
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TRPV4 Q9HBA0 2/20 0.35
▸ LRRK2 Q5S007 2/20 0.34
▸ GRM4 Q14833 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28866660 0.84 NFE2L2 (0.40) NFE2L2CCR4MEN1KMT2ALRRK2
Hydrochloric Acid SCHEMBL28293560 0.83 NFE2L2 (0.40) NFE2L2CCR4MEN1KMT2ALRRK2
SCHEMBL30360826 0.82 TRPV4 (0.39) NFE2L2CCR4MEN1KMT2ATRPV4
SCHEMBL7864574 0.82 TRPV4 (0.39) NFE2L2CCR4MEN1KMT2ATRPV4
SCHEMBL31188398 0.77 SLC40A1 (0.34) —
SCHEMBL31121359 0.77 SLC22A12 (0.44) NFE2L2CCR4MEN1KMT2ATRPV4
SCHEMBL4394771 0.77 SLC22A12 (0.44) NFE2L2CCR4MEN1KMT2ATRPV4
SCHEMBL31121360 0.77 SLC22A12 (0.44) NFE2L2CCR4MEN1KMT2ATRPV4
SCHEMBL5937359 0.75 TDP1 (0.34) NFE2L2SMN1; SMN2
SCHEMBL30953866 0.75 ESR1 (0.40) NFE2L2CCR4MEN1KMT2ATRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1159297-C N-([1,2,4]triazoleo azine group) benzene sulfonamide and pyridine sulfamide compound and their use as herbicide ��ũҵ��ѧ��˾ 2004-07-28 — — CN disclosed
CN-1397551-A N-([1,2,4]triazoleo azine group) benzene sulfonamide and pyridine sulfamide compound and their use as herbicide DOW AGROSCIENCES CORP (US) 2003-02-19 — — CN disclosed
CN-1092195-C N- ([1,2,4] triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2002-10-09 — — CN disclosed
US-6303814-B1 N-[1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC 2001-10-16 — — US disclosed
EP-0877745-B1 N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 2001-07-25 — — EP disclosed
US-6130335-A N-([1,2,4]triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 2000-10-10 — — US disclosed
US-6005108-A POST-EMERGENCE TOTAL VEGETATION CONTROL OR SELECTIVE CONTROL OF WEEDS IN WHEAT, RICE AND OIL-SEED RAPE CROPS JOHNSON TIMOTHY C (US) 1999-12-21 — — US disclosed
US-5965490-A NOVEL COMPOUNDS WITH IMPROVED SELECTIVITY TO VALUABLE CROPS AND IMPROVED TOXICOLOGICAL AND ENVIRONMENTAL ATTRIBUTES; APPLYING TO CONTROL WEEDS BY EITHER PREEMERGENCE OR POSTEMERGENCE APPLICATION DOW AGROSCIENCES LLC (US) 1999-10-12 — — US disclosed
CN-1206416-A N- ([1,2,4] triazoloazinyl) benzenesulfonamide and pyridinesulfonamide compounds and their use as herbicides DOW AGROSCIENCES LLC (US) 1999-01-27 — — CN disclosed
EP-0877745-A2 N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES Dow Agrosciences LLC (US) 1998-11-18 — — EP disclosed
WO-1998013367-A1 N-([1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES DOW AGROSCIENCES LLC (US) 1998-04-02 — — WO disclosed
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