SCHEMBL303613

SCHEMBL303613

CCCC[CH]c1cccc2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CHAT P28329 4/20 0.48
CNR1 P21554 2/20 0.48
GAA P10253 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTR1B P28222 1/20 0.40
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
KDM4E B2RXH2 1/20 0.39
RXRA P19793 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL304242 0.95 CHAT (0.50) CHATCNR1GAATDP1L3MBTL1
SCHEMBL304218 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL303925 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL302714 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL303784 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL303905 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL302668 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL303704 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL302934 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1
SCHEMBL304715 0.93 CHAT (0.52) CHATCNR1GAATDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 436 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1038863-B1 Substituted dimeric compounds, process for their preparation and pharmaceutical compositions thereof SERVIER LAB (FR) 2003-06-04 EP claimed
EP-1057826-B1 Substituted dimeric carboxamide derivatives, method for preparing them, and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-04-16 EP claimed
EP-4234609-B1 METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS POLYPLUS TRANSFECTION (FR) 2024-07-17 EP disclosed
EP-4019607-B1 ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM ESSILOR INT (FR) 2024-05-15 EP disclosed
US-20240052235-A1 ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM ESSILOR INTERNATIONAL (FR) 2024-02-15 US disclosed
CN-117551696-A Composition for transfecting nucleic acid molecules into cells comprising triazole compounds grafted onto cationic polymers and uses thereof 宝利普拉斯生物转染公司 2024-02-13 CN disclosed
CN-114901316-B Composition for transfecting nucleic acid molecules into cells comprising triazole compounds grafted onto cationic polymers and uses thereof 宝利普拉斯生物转染公司 2024-02-13 CN disclosed
US-11879001-B2 Conjugate comprising an IL-2 moiety Ascendis Pharma Oncology Division A/S (DK) 2024-01-23 US disclosed
US-20230340055-A1 GLYCOSYLATED IL-2 PROTEINS AND USES THEREOF Ascendis Pharma Oncology Division A/S (DK) 2023-10-26 US disclosed
CN-116783168-A Electrochromic compounds and optical articles comprising the same 依视路国际公司 2023-09-19 CN disclosed
WO-2023161409-A1 METHODS FOR PURIFICATION, DETECTION AND QUANTIFICATION OF RESIDUAL PEI-BASED TRANSFECTION REAGENTS POLYPLUS TRANSFECTION (FR) 2023-08-31 WO disclosed
WO-1993009077-A2 PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS ABBOTT LABORATORIES (US) 1993-05-13 WO disclosed
EP-0503785-A1 1-Biphenylimidazole derivatives, their preparation and their therapeutic use Sankyo Company Limited (JP) 1992-09-16 EP disclosed
EP-0501656-A2 New benzene derivatives having (NGF) production-promoting activity Sankyo Company Limited (JP) 1992-09-02 EP disclosed
EP-0498680-A1 New beta-amino-alpha-hydroxycarboxylic acids and their use Sankyo Company Limited (JP) 1992-08-12 EP disclosed
WO-1992009564-A1 PEPTIDYL DERIVATIVES CELLTECH LIMITED (GB) 1992-06-11 WO disclosed
WO-1992009565-A1 PEPTIDYL DERIVATIVES CELLTECH LIMITED (GB) 1992-06-11 WO disclosed
EP-0489577-A1 Peptidyl derivatives CELLTECH LIMITED (GB) 1992-06-10 EP disclosed
EP-0489579-A1 Peptidyl derivatives CELLTECH THERAPEUTICS LIMITED (GB) 1992-06-10 EP disclosed
US-4329350-A VASODILATORS RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) 1982-05-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230340055-A1 GLYCOSYLATED IL-2 PROTEINS AND USES THEREOF IL2, IL1A, ILF2 CHAT 2571/4885CNR1 4767/4885GAA 1133/4885
US-11879001-B2 Conjugate comprising an IL-2 moiety IL2, IL2RA, IL4I1 CHAT 2626/4885CNR1 4105/4885GAA 4063/4885
US-20240052235-A1 ELECTROCHROMIC COMPOUNDS AND OPTICAL ARTICLES CONTAINING THEM EYA3, LAGE3, CDKL5 CHAT 153/4885CNR1 1691/4885GAA 4365/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.