Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20305540 | 0.81 | POLB (0.64) | POLBMEN1KMT2AAPEX1MAOA | |
| SCHEMBL11171813 | 0.79 | ALDH1A1 (0.47) | POLBMEN1KMT2AAPEX1MAOA | |
| SCHEMBL230414 | 0.74 | KDM4E (0.50) | POLBMEN1KMT2AMAOAMAPT | |
| SCHEMBL8321902 | 0.71 | POLB (0.81) | POLBMEN1KMT2AAPEX1MAOA | |
| SCHEMBL20321153 | 0.71 | POLB (0.59) | POLBMEN1KMT2AAPEX1MAOA | |
| SCHEMBL9544841 | 0.69 | POLB (1.00) | POLBMEN1KMT2AAPEX1TSHR | |
| SCHEMBL9630573 | 0.66 | POLB (0.53) | POLBMEN1KMT2AAPEX1TSHR | |
| SCHEMBL2556802 | 0.66 | MEN1 (0.70) | POLBMEN1KMT2AAPEX1HSD17B10 | |
| SCHEMBL486184 | 0.66 | MEN1 (1.00) | POLBMEN1KMT2AAPEX1MAPT | |
| SCHEMBL3033442 | 0.66 | CYP2C19 (0.41) | POLBKMT2ATSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101801913-B | Method for producing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG | 2014-06-11 | — | — | CN | disclosed |
| EP-2203410-B1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2014-03-26 | — | — | EP | disclosed |
| EP-2253610-B1 | Method for manufacturing of enaminocarbonyl-compounds and their use in preparing 4-aminobut-2-enolids | BAYER CROPSCIENCE AG (DE) | 2013-11-20 | — | — | EP | disclosed |
| US-8487112-B2 | Method for producing 4-aminobut-2-enolides | BAYER CROPSCIENCE AG (DE) | 2013-07-16 | — | — | US | disclosed |
| EP-2253610-A1 | Method for manufacturing 4-aminobut-2-enolids | Bayer CropScience AG (DE) | 2010-11-24 | — | — | EP | disclosed |
| US-20100204480-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE (DE) | 2010-08-12 | — | — | US | disclosed |
| EP-2203410-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | Bayer CropScience AG (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009036898-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | BAYER CROPSCIENCE AG (DE) | 2009-03-26 | — | — | WO | disclosed |
| EP-2039678-A1 | Method for manufacturing 4-aminobut-2-enolids | Bayer CropScience AG (DE) | 2009-03-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204480-A1 | METHOD FOR PRODUCING 4-AMINOBUT-2-ENOLIDES | CYP4B1, TUBB4B, EIF4B | POLB 753/4885MEN1 2703/4885KMT2A 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.