Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GALK1 | P51570 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PLEC | Q15149 | 1/20 | 0.42 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12869192 | 0.91 | POLB (0.83) | POLBKMT2AMEN1APEX1MAPT | |
| SCHEMBL8321902 | 0.89 | POLB (0.81) | POLBKMT2AMEN1APEX1MAPT | |
| SCHEMBL9999989 | 0.83 | POLB (0.71) | POLBKMT2AMEN1APEX1ALDH1A1 | |
| SCHEMBL20305540 | 0.78 | POLB (0.64) | POLBKMT2AMEN1APEX1MAPT | |
| SCHEMBL7285810 | 0.78 | POLB (0.63) | POLBKMT2AMEN1APEX1MAPT | |
| SCHEMBL12869177 | 0.75 | POLB (0.61) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL20321153 | 0.75 | POLB (0.59) | POLBKMT2AMEN1APEX1MAPT | |
| SCHEMBL2893384 | 0.74 | POLB (0.58) | POLBKMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL2033213 | 0.73 | MT-CO2 (0.69) | POLBKMT2AMEN1MAPTMAPK1 | |
| SCHEMBL6248215 | 0.73 | POLB (0.57) | POLBKMT2AMEN1APEX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5051317-A | — | — | None | — | — | JP | disclosed |
| JP-H0551317-A | MEDICINE FOR IMPROVEMENT OF BRAIN FUNCTION | NIKKEN CHEM CO LTD | 1993-03-02 | — | — | JP | disclosed |