Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1968022 | 0.86 | KMT2A (0.48) | PARP1POLBPKMDRD4PRNP | |
| SCHEMBL318081 | 0.82 | DRD4 (0.39) | PARP1POLBPKMDRD4CNR2 | |
| SCHEMBL1966404 | 0.80 | DRD4 (0.51) | POLBDRD4CNR2PRNPKMT2A | |
| SCHEMBL1966068 | 0.77 | KCNA5 (0.41) | CNR2LMNAHPGDTSHRKMT2A | |
| SCHEMBL304739 | 0.76 | CNR2 (0.43) | POLBCNR2LMNAKMT2AMEN1 | |
| SCHEMBL3263279 | 0.75 | DRD4 (0.50) | PARP1POLBPKMDRD4KMT2A | |
| SCHEMBL3230248 | 0.74 | LMNA (0.57) | PARP1LMNAHPGDTSHRKMT2A | |
| SCHEMBL3376941 | 0.73 | POLB (0.49) | POLBPKMPRNPKMT2AMEN1 | |
| SCHEMBL3260086 | 0.72 | TSHR (0.39) | CNR2LMNAHPGDTSHRKMT2A | |
| SCHEMBL1976194 | 0.72 | CNR2 (0.39) | CNR2LMNAHPGDTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2012500835-A | — | — | 2012-01-12 | — | — | JP | claimed |
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | claimed |