Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PRNP | P04156 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377457 | 0.92 | MAPT (0.40) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL3378121 | 0.85 | MAPT (0.46) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL3378020 | 0.85 | MEN1 (0.55) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL3376941 | 0.79 | POLB (0.49) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL3376222 | 0.79 | MAPT (0.45) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL302013 | 0.76 | POLB (0.43) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL3376229 | 0.76 | ALDH1A1 (0.53) | ALDH1A1POLBMAPTGAALMNA | |
| SCHEMBL3377134 | 0.76 | KMT2A (0.42) | MEN1KMT2AALDH1A1MAPTGAA | |
| SCHEMBL303525 | 0.74 | KMT2A (0.53) | MEN1KMT2APOLBMAPTPRNP | |
| SCHEMBL302098 | 0.73 | KEAP1 (0.49) | MEN1KMT2AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342177-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-07-13 | — | — | EP | disclosed |