Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 3/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL318081 | 0.86 | DRD4 (0.39) | DRD4CNR2KMT2ADRD3DRD2 | |
| SCHEMBL306481 | 0.80 | PARP1 (0.42) | DRD4CNR2KMT2APOLBTRPV1 | |
| SCHEMBL3263279 | 0.78 | DRD4 (0.50) | DRD4KMT2ADRD3DRD2HTR1A | |
| SCHEMBL1968022 | 0.78 | KMT2A (0.48) | DRD4KMT2ADRD3DRD2HTR1A | |
| SCHEMBL3376941 | 0.77 | POLB (0.49) | KMT2APOLBPRNPMEN1MAPT | |
| SCHEMBL302209 | 0.77 | CNR2 (0.51) | CNR2KMT2ADRD3HTR1AHTR2A | |
| SCHEMBL3263275 | 0.77 | TSHR (0.50) | DRD4KMT2APOLBTRPV1MEN1 | |
| SCHEMBL302050 | 0.76 | HTR2C (0.53) | CNR2KMT2ADRD3HTR1AHTR2A | |
| SCHEMBL303627 | 0.74 | HTR2C (0.39) | DRD4CNR2KMT2ADRD3DRD2 | |
| SCHEMBL301830 | 0.74 | HTR2C (0.61) | CNR2KMT2ADRD3HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2334637-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-06-22 | — | — | EP | disclosed |