SCHEMBL3036292

SCHEMBL3036292

O=C(Cl)c1ccccc1N1C(=O)C=CC1=O

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.64
TLR9 Q9NR96 3/20 0.64
HSP90AA1 P07900 2/20 0.64
ATM Q13315 2/20 0.64
NPSR1 Q6W5P4 2/20 0.64
PKM P14618 1/20 0.64
CCR6 P51684 1/20 0.64
TDP1 Q9NUW8 1/20 0.64
MGLL Q99685 11/20 0.55
MITF O75030 1/20 0.50
HTT P42858 1/20 0.50
FAAH O00519 2/20 0.46
ALOX15 P16050 2/20 0.44
GAA P10253 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29364136 0.82 ALDH1A1 (0.71) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL183052 0.82 ALDH1A1 (0.71) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL7165238 0.81 TLR9 (0.64) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL29510541 0.81 TLR9 (0.64) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL11324489 0.81 TLR9 (0.64) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL9240798 0.81 TLR9 (0.64) ALDH1A1TLR9HSP90AA1ATMNPSR1
Hydrochloric Acid SCHEMBL6753288 0.81 ALDH1A1 (0.69) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL10938557 0.81 ALDH1A1 (0.64) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL28267017 0.80 ALDH1A1 (0.60) ALDH1A1TLR9HSP90AA1ATMNPSR1
SCHEMBL2210131 0.79 APEX1 (0.53) ALDH1A1TLR9HSP90AA1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104031354-B Resin combination and use its prepreg made and laminate 苏州生益科技有限公司 2016-08-03 CN disclosed
US-8765012-B2 Thermosetting composition and printed circuit board using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2014-07-01 US disclosed
US-20100147689-A1 METHOD FOR MODIFYING SURFACE OF ALUMINUM OXIDE AND ELECTROOSMOSIS PUMP AND ELECTRIC POWER GENERATOR USING MODIFIED ALUMINUM OXIDE MEMBRANE INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-06-17 US disclosed
US-20100124037-A1 THERMOSETTING COMPOSITION AND PRINTED CIRCUIT BOARD USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-05-20 US disclosed
US-7655155-B2 Liquid crystal thermoset monomer or oligomer, thermosetting liquid crystal polymer composition comprising the same and printed circuit board using the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-02-02 US disclosed
US-20090224203-A1 LIQUID CRYSTAL THERMOSET MONOMER OR OLIGOMER, THERMOSETTING LIQUID CRYSTAL POLYMER COMPOSITION COMPRISING THE SAME AND PRINTED CIRCUIT BOARD USING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-09-10 US disclosed
US-6709679-B2 CONSISTING OF NATIVE OR THIOLATED TRANSFERRIN OR ALBUMIN OR OF POLYETHYLENE GLYCOL WITH ATLEAST ONE MERCAPTAN, HYDROXY OR AMINE GROUP AND CYTOSTATIC COMPOUNDS DERIVED THROUGH MALEINIMIDE OR HYDROXYSUCCINIMIDE ESTER COMPOUNDS KRATZ FELIX (DE) 2004-03-23 US disclosed
US-20020019343-A1 Antineoplastic conjugates of transferrin, albumin and polyethylene glycol KRATZ FELIX (DE) 2002-02-14 US disclosed
US-6310039-B1 TUMOR-INHIBITING CONJUGATES OF PROTEINS AND POLYMERS CONSISTING OF A SUITABLE CARRIER SYSTEM AND CYTOSTATIC COMPOUNDS KRATZ FELIX (DE) 2001-10-30 US disclosed
US-6001958-A POLYMER HAS ON AT LEAST TWO OF ITS ENDS, AT LEAST ONE REACTIVE END GROUP OF A DIFFERENT CHEMICAL TYPE FROM THAT OF THE GROUP PREDOMINANTLY USED IN POLYMERIZATION AND THE PREPARATION OF A POLYMER SKELETON. FLAMEL TECHNOLOGIES (FR) 1999-12-14 US disclosed
US-5811507-A Polyesterimides for use in linear and/or non-linear optics, and one method for preparing same FLAMEL TECHNOLOGIES (FR) 1998-09-22 US disclosed
WO-1996000395-A1 EVALUATION OF BLOOD COAGULATION ACTIVITY CHEMTRAK, INC. (US) 1996-01-04 WO disclosed
US-4269966-A A MIXTURE OF AN ACRYLIC COMPOUND CONTAINING IMIDE, AMIDE, AND AN AMINE GROUP; MOLDING MATERIAL; CROSSLINKED, INSOLUBLE, INFUSIBLE POLYMER TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1981-05-26 US disclosed
US-4239883-A INFUSIBLE AND INSOLUBLE TECHNOCHEMIE GMBH VERFAHRENSTECHNIK (DE) 1980-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020019343-A1 Antineoplastic conjugates of transferrin, albumin and polyethylene glycol TFRC, ALB, FOLR1 ALDH1A1 2933/4885TLR9 155/4885HSP90AA1 286/4885
US-20090224203-A1 LIQUID CRYSTAL THERMOSET MONOMER OR OLIGOMER, THERMOSETTING LIQUID CRYSTAL POLYMER COMPOSITION COMPRISING THE SAME AND PRINTED CIRCUIT BOARD USING THE SAME MLLT1, RCC1, CNOT1 ALDH1A1 2509/4885TLR9 2254/4885HSP90AA1 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.