SCHEMBL30366242

SCHEMBL30366242

Cc1ccc(C)c(CBr)c1CBr

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TRPA1 O75762 1/20 0.32
ACHE P22303 1/20 0.32
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13367148 1.00 CYP1A2 (0.33) CYP1A2TSHRALDH1A1TRPA1ACHE
SCHEMBL10752183 0.85 CYP1A2 (0.32) CYP1A2TSHR
SCHEMBL1072053 0.81 CYP2A6 (0.43) CYP1A2TSHRALDH1A1TRPA1ACHE
SCHEMBL2258690 0.78 HAAO (0.40) CYP1A2ALDH1A1
SCHEMBL15352385 0.77 ACHE (0.32) ACHE
SCHEMBL4161396 0.75 NQO1 (0.35) ALDH1A1
SCHEMBL1230326 0.74 TSHR (0.54) CYP1A2TSHRALDH1A1
SCHEMBL1690405 0.74
SCHEMBL4868173 0.74 L3MBTL1 (0.38) CYP1A2ALDH1A1ACHE
SCHEMBL6217138 0.73 ALDH1A1 (0.50) CYP1A2TSHRALDH1A1TRPA1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115991624-A Method for producing tetratoluene 中国石油化工股份有限公司 2023-04-21 CN disclosed