SCHEMBL13367148

SCHEMBL13367148

Cc1ccc(C)c(CBr)c1CBr

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
TSHR P16473 2/20 0.32
ALDH1A1 P00352 2/20 0.32
TRPA1 O75762 1/20 0.32
ACHE P22303 1/20 0.32
NOS3 P29474 1/20 0.31
NOS2 P35228 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10752183 0.85 CYP1A2 (0.32) CYP1A2TSHR
SCHEMBL1072053 0.81 CYP2A6 (0.43) CYP1A2TSHRALDH1A1TRPA1ACHE
SCHEMBL2258690 0.78 HAAO (0.40) CYP1A2ALDH1A1
SCHEMBL15352385 0.77 ACHE (0.32) ACHE
SCHEMBL4161396 0.75 NQO1 (0.35) ALDH1A1
SCHEMBL1230326 0.74 TSHR (0.54) CYP1A2TSHRALDH1A1
SCHEMBL1690405 0.74
SCHEMBL4868173 0.74 L3MBTL1 (0.38) CYP1A2ALDH1A1ACHE
SCHEMBL6217138 0.73 ALDH1A1 (0.50) CYP1A2TSHRALDH1A1TRPA1ACHE
SCHEMBL3188982 0.73 ALDH1A1 (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11260379-B2 Catalysts and methods for epoxide-based polymerizations CORNELL UNIVERSITY (US) 2022-03-01 US disclosed
US-20200384450-A1 CATALYSTS AND METHODS FOR EPOXIDE-BASED POLYMERIZATIONS CORNELL UNIVERSITY 2020-12-10 US disclosed
US-20200384450-A1 CATALYSTS AND METHODS FOR EPOXIDE-BASED POLYMERIZATIONS CORNELL UNIVERSITY 2020-12-10 US disclosed
US-9944663-B2 Process for preparing substituted pentacenes MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2018-04-17 US disclosed
US-8318048-B2 Process for preparing substituted pentacenes MERCK PATENT GMBH (DE) 2012-11-27 US disclosed
US-20100127220-A1 Process for Preparing Substituted Pentacenes MERCK PATENT GMBH (DE) 2010-05-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100127220-A1 Process for Preparing Substituted Pentacenes FES, PFAS, SLC46A1 CYP1A2 1513/4885TSHR 1010/4885ALDH1A1 1737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.