Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 10/20 | 0.43 |
| ▸ | KDR | P35968 | 10/20 | 0.43 |
| ▸ | LCK | P06239 | 10/20 | 0.40 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 3/20 | 0.36 |
| ▸ | SRC | P12931 | 4/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | NUDT14 | O95848 | 1/20 | 0.34 |
| ▸ | NUDT5 | Q9UKK9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30366958 | 0.86 | ALOX5AP (0.43) | TEKKDRRETSRCBTK | |
| SCHEMBL30366769 | 0.81 | KDR (0.35) | TEKKDRLCKTNK2RET | |
| SCHEMBL25716096 | 0.79 | TEK (0.53) | TEKKDRLCKRETSRC | |
| SCHEMBL30366523 | 0.75 | KDR (0.33) | TEKKDRLCKTNK2RET | |
| SCHEMBL30366702 | 0.73 | BTK (0.39) | TEKKDRLCKBTKFFAR4 | |
| SCHEMBL30367019 | 0.73 | ALOX5AP (0.48) | EIF2AK3 | |
| SCHEMBL28981125 | 0.70 | TGFBR1 (0.41) | TEKKDRLCKSRC | |
| SCHEMBL22676145 | 0.69 | LRRK2 (0.43) | TEKKDRLCKSRCBTK | |
| SCHEMBL25714787 | 0.68 | KDM4E (0.37) | BTK | |
| SCHEMBL16483429 | 0.67 | FFAR4 (0.47) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115894481-A | Nitrogen-containing heteroaryl compound, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2023-04-04 | — | — | CN | disclosed |